Differential hydration of homopurine sequences relative to alternating purine/pyrimidine sequences

The minor groove ligand distamycin A has been used to probe the relative hydration of the minor groove of eight synthetic polynucleotides of known sequence and composition. A combination of densimetric, calorimetric, and temperature‐dependent spectroscopic techniques have been used to obtain complet...

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Veröffentlicht in:	Biopolymers 1992-08, Vol.32 (8), p.1065-1075
Hauptverfasser:	Rentzeperis, Dionisios, Kupke, Donald W., Marky, Luis A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Base Sequence Biological and medical sciences Calorimetry Distamycins - metabolism Fundamental and applied biological sciences. Psychology Molecular biophysics Netropsin - metabolism Physico-chemical properties of biomolecules Polynucleotides - chemistry Purines - chemistry Purines - metabolism Pyrimidines - chemistry Pyrimidines - metabolism Thermodynamics Water - chemistry
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