Overexpression of the Mammalian Target of Rapamycin: A Novel Biomarker for Poor Survival in Resected Early Stage Non-small Cell Lung Cancer

The best hope of cure for patients with non-small cell lung cancer (NSCLC) is surgical resection. However, even in stage IA patients, 30% die within 5 years. Further improvements in survival require a biomarker(s), which defines the subset of these patients destined to do badly so that they could be...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Journal of thoracic oncology 2010-03, Vol.5 (3), p.314-319
Hauptverfasser:	Dhillon, Tony, Mauri, Francesco A., Bellezza, Guido, Cagini, Lucio, Barbareschi, Mattia, North, Bernard V., Seckl, Michael J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenocarcinoma - metabolism Adenocarcinoma - mortality Adenocarcinoma - pathology Adenocarcinoma, Bronchiolo-Alveolar - metabolism Adenocarcinoma, Bronchiolo-Alveolar - mortality Adenocarcinoma, Bronchiolo-Alveolar - pathology Adult Aged Aged, 80 and over Biomarker Carcinoma, Large Cell - metabolism Carcinoma, Large Cell - mortality Carcinoma, Large Cell - pathology Carcinoma, Neuroendocrine - metabolism Carcinoma, Neuroendocrine - mortality Carcinoma, Neuroendocrine - pathology Carcinoma, Non-Small-Cell Lung - metabolism Carcinoma, Non-Small-Cell Lung - mortality Carcinoma, Non-Small-Cell Lung - pathology Carcinoma, Squamous Cell - metabolism Carcinoma, Squamous Cell - mortality Carcinoma, Squamous Cell - pathology Female Humans Immunoenzyme Techniques Intracellular Signaling Peptides and Proteins - metabolism Lung Neoplasms - metabolism Lung Neoplasms - mortality Lung Neoplasms - pathology Male Middle Aged mTOR Neoplasm Invasiveness Neoplasm Staging Non-small cell lung cancer Prognosis Protein-Serine-Threonine Kinases - metabolism Survival Rate Tissue Array Analysis TOR Serine-Threonine Kinases
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!