The role of PTEN-FAK signaling pathway in metastasis and invasive ability of leukemia cells

To investigate the effect of the wild type phosphatase and tensin homolog deleted on chromosome 10 (PTEN), a tumor-suppressor gene on the proliferation and apoptosis of human chronic myeloid leukemia (CML) cells line (K562) in vitro and explore the influence of PTEN-FAK signaling pathway on invasion...

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Veröffentlicht in:	Zhōnghuá xuèyèxué zázhì 2009-02, Vol.30 (2), p.115-120
Hauptverfasser:	Cheng, Zhi-yong, Guo, Xiao-ling, Li, Shi-hui, Wang, Su-yun, Yang, Xiao-yang, Xue, Fang, Wen, Shu-peng, Pan, Ling
Format:	Artikel
Sprache:	chi
Schlagworte:	Apoptosis Cell Movement Cell Proliferation Focal Adhesion Kinase 1 - genetics Focal Adhesion Kinase 1 - metabolism Genetic Vectors Humans K562 Cells Leukemic Infiltration PTEN Phosphohydrolase - genetics PTEN Phosphohydrolase - metabolism Signal Transduction Transfection
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