Stable transfection of calbindin-D28k into the GH3 cell line alters calcium currents and intracellular calcium homeostasis

Previous work demonstrating the presence and differential distribution of Ca(2+)-binding proteins in the CNS has led to the proposal that cytosolic proteins, such as calbindin-D28k (CB), may play a pivotal role in neurons. We have used a retrovirus containing the full-length cDNA for CB to transfect...

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Veröffentlicht in:	Neuron (Cambridge, Mass.) Mass.), 1992-11, Vol.9 (5), p.943-954
Hauptverfasser:	LLEDO, P.-M, SOMASUNDARAM, B, MORTON, A. J, EMSON, P. C, MASON, W. T
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Calbindin 1 Calbindins Calcium - metabolism Calcium Channels - physiology Cell Membrane - physiology Cell physiology Chelating Agents - pharmacology Electric Conductivity Fundamental and applied biological sciences. Psychology Gene Expression Genetic Vectors Homeostasis - physiology Membrane and intracellular transports Molecular and cellular biology Pituitary Neoplasms Rats Retroviridae - genetics S100 Calcium Binding Protein G - genetics S100 Calcium Binding Protein G - physiology Transfection Tumor Cells, Cultured
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