Cloning of the human cholesterol 7 α-hydroxylase gene ( CYP7) and localization to chromosome 8q11–q12

Cholesterol 7 α-hydroxylase (7 α-hydroxylase) is a microsomal cytochrome P450 that catalyzes the first step in bile acid synthesis. In this paper, we describe the cloning, characterization, and chromosomal mapping of the human 7 α-hydroxylase gene ( CYP7). The gene spans 10 kb and contains six exons...

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Veröffentlicht in:	Genomics (San Diego, Calif.) Calif.), 1992-09, Vol.14 (1), p.153-161
Hauptverfasser:	Cohen, Jonathan C., Cali, James J., Jelinek, Diane F., Mehrabian, Margarete, Sparkes, Robert S., Lusis, Aldons J., Russell, David W., Hobbs, Helen H.
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Animals Biological and medical sciences Blotting, Southern cholesterol 7 alpha -monooxygenase Cholesterol 7-alpha-Hydroxylase - genetics chromosome 8 Chromosome Mapping Chromosomes, Human, Pair 8 Cloning, Molecular Exons - genetics Fundamental and applied biological sciences. Psychology Gene Frequency genes Genes. Genome Humans Hybrid Cells Introns - genetics man mapping Mice Molecular and cellular biology Molecular genetics Molecular Sequence Data Nucleic Acid Hybridization Pedigree Polymorphism, Genetic Polymorphism, Restriction Fragment Length Sequence Homology
Online-Zugang:	Volltext
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