Expression of ADAM‐9 mRNA and protein in human breast cancer

The ADAMs (a disintegrin and metalloprotease) are membrane proteins containing both protease and adhesion domains and thus may be potentially important in cancer invasion and metastasis. The aim of our study was to investigate the distribution and potential clinical significance of ADAM‐9 in breast...

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Veröffentlicht in:	International journal of cancer 2003-07, Vol.105 (6), p.754-761
Hauptverfasser:	O'Shea, Caroline, McKie, Norman, Buggy, Yvonne, Duggan, Catherine, Hill, Arnold D.K, McDermott, Enda, O'Higgins, Niall, Duffy, Michael J.
Format:	Artikel
Sprache:	eng
Schlagworte:	ADAM Proteins ADAMs ADAM‐9, HER‐2/neu Biological and medical sciences Blotting, Western Breast - metabolism breast cancer Breast Neoplasms - diagnosis Breast Neoplasms - genetics Breast Neoplasms - metabolism Carcinoma - diagnosis Carcinoma - genetics Carcinoma - metabolism Disintegrins Female Fibroadenoma - genetics Fibroadenoma - metabolism Gynecology. Andrology. Obstetrics Humans Mammary gland diseases Medical sciences Membrane Proteins - genetics Membrane Proteins - metabolism Metalloendopeptidases metastasis Middle Aged Muscle Proteins - genetics Muscle Proteins - metabolism Prognosis RNA, Messenger - biosynthesis RNA, Neoplasm - biosynthesis Tissue Distribution Tumor Cells, Cultured Tumors
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