HCO3−-Dependent Intracellular pH Regulation in the Premature Myocardium

This study investigated developmental changes in Na+-H+ exchange and HCO3 -Cl exchange activities in newborn and adult rabbit hearts. pHi was measured using the fluorescent dye 2ʼ,7ʼ-bis(2-carboxyethyl)-5(6)-carboxyfluorescein in isolated myocytes. Myocardial mechanical function was measured in the...

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Veröffentlicht in:	Circulation research 1992-12, Vol.71 (6), p.1314-1323
Hauptverfasser:	Nakanishi, Toshio, Gu, Hong, Seguchi, Masashi, Cragoe, Edward J, Momma, Kazuo
Format:	Artikel
Sprache:	eng
Schlagworte:	4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid - pharmacology Acidosis, Respiratory - metabolism Age Factors Amiloride - analogs & derivatives Amiloride - pharmacology Animals Animals, Newborn - metabolism Bicarbonates - metabolism Biological and medical sciences Chlorides - metabolism Fundamental and applied biological sciences. Psychology Heart Heart - drug effects Hydrogen-Ion Concentration In Vitro Techniques Myocardium - cytology Myocardium - metabolism Rabbits Sodium - metabolism Vertebrates: cardiovascular system
Online-Zugang:	Volltext
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