Lack of inhibition of ornithine decarboxylase activity by ibuprofen

The influence of the anti-inflammatory drug ibuprofen on the activity of ornithine decarboxylase (ODC, EC 4.1.1.17), the key enzyme of polyamine synthesis, was studied using a 20,000 g supernatant of rat testis and regenerating liver homogenates as sources of the enzyme. Ibuprofen, in all concentrat...

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Veröffentlicht in:	Pharmacological research 1992-05, Vol.25 (4), p.347-352
Hauptverfasser:	VESELA, J, SEMECKY, V, DRSATA, J
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Bones, joints and connective tissue. Antiinflammatory agents Eflornithine - pharmacology Ibuprofen - pharmacology Liver - enzymology Male Medical sciences Ornithine Decarboxylase - metabolism Ornithine Decarboxylase Inhibitors Pharmacology. Drug treatments Rats Rats, Wistar Testis - enzymology
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