Oxidative Stress Caused by Inactivation of Glutathione Peroxidase and Adaptive Responses

Reactive oxygen species (ROS) are generated as by-products of cellular metabolism, primarily in the mitochondria. When the cellular production of ROS exceeds the cell's antioxidant capacity, cellular macromolecules such as lipids, proteins and DNA can be damaged. Because of this, 'oxidativ...

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Veröffentlicht in:	Biological chemistry 2003-04, Vol.384 (4), p.567-574
Hauptverfasser:	Miyamoto, Y., Koh, Y. H., Park, Y. S., Fujiwara, N., Sakiyama, H., Misonou, Y., Ookawara, T., Suzuki, K., Honke, K., Taniguchi, N.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adaptation, Physiological - physiology Aldehydes - metabolism Animals Fructose - metabolism Glutathione Peroxidase - metabolism Humans Nitric Oxide - metabolism Nitric Oxide - physiology Oxidative Stress - physiology
Online-Zugang:	Volltext
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