Plasmodium berghei: Sporozoites are sensitive to human serum but not susceptible host serum

Human complement was activated by rodent malaria, Plasmodium berghei, sporozoites through the alternative pathway, as revealed by C3 deposition on sporozoites using the fluorescent antibody technique. Sporozoites exposed to fresh human serum decreased in infectivity to HepG2 cells, but those exposed...

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Veröffentlicht in:	Experimental parasitology 1992-11, Vol.75 (4), p.361-368
Hauptverfasser:	Kawamoto, Yasuko, Winger, Larry A., Hong, Kyongsu, Matsuoka, Hiroyuki, Chinzei, Yasuo, Kawamoto, Fumihiko, Kamimura, Kiyoshi, Arakawa, Ryo, Sinden, Robert E., Miyama, Akio
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences C3 deposition Complement Activation Complement C3 - pharmacology Complement Pathway, Alternative Complement System Proteins - pharmacology Disease Susceptibility Experimental protozoal diseases and models HepG2 cell Humans Immunofluorescence Infectious diseases Liver - cytology Liver - parasitology Malaria - immunology Malaria - veterinary Medical sciences Mice Parasitic diseases Plasmodium berghei Plasmodium berghei - drug effects Plasmodium berghei - immunology Protozoal diseases Sporozoite Tumor Cells, Cultured
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