Behavioral effects of neonatal and adult excitotoxic lesions of the mediodorsal thalamus in the adult rat

We examined in the rat, the effects of neonatal (postnatal Day 7) and adult excitotoxic lesions of the mediodorsal thalamus (MDT), a brain area innervating the prefrontal cortex and implicated as a site of neuropathology in schizophrenia. Previous studies showed that rats with neonatal excitotoxic d...

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Veröffentlicht in:	Behavioural brain research 2003-05, Vol.141 (2), p.105-111
Hauptverfasser:	Lipska, Barbara K., Luu, Suly, Halim, Nader D., Weinberger, Daniel R.
Format:	Artikel
Sprache:	eng
Schlagworte:	Aging - physiology Aging - psychology Amphetamine Anatomical correlates of behavior Animals Animals, Newborn - physiology Behavior, Animal - physiology Behavioral psychophysiology Biological and medical sciences Development Dopamine - physiology Female Fundamental and applied biological sciences. Psychology Ibotenic acid Locomotion Male Motor Activity - physiology Prefrontal cortex Pregnancy Psychology. Psychoanalysis. Psychiatry Psychology. Psychophysiology Rats Rats, Sprague-Dawley Schizophrenia - physiopathology Stress Thalamus - anatomy & histology Thalamus - physiology Ventral hippocampus
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