Effect of moderate exercise on rat T-cells
The aim of this study was a detailed examination of the effects of moderate exercise on T-cells in adult male Wistar rats. The T-cell populations were compared in sedentary rats (C, n = 5) and in rats trained for 4 weeks on a treadmill (30-60 min.day-1, 6 days.week-1, 20-30 m.min-1) and sacrificed a...
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| Veröffentlicht in: | European Journal of Applied Physiology and Occupational Physiology 1992-11, Vol.65 (5), p.464-468 |
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| container_title | European Journal of Applied Physiology and Occupational Physiology |
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| creator | FERRY, A RIEU, P LAZIRI, F EL HABAZI, A LE PAGE, C RIEU, M |
| description | The aim of this study was a detailed examination of the effects of moderate exercise on T-cells in adult male Wistar rats. The T-cell populations were compared in sedentary rats (C, n = 5) and in rats trained for 4 weeks on a treadmill (30-60 min.day-1, 6 days.week-1, 20-30 m.min-1) and sacrificed at rest (T-rest, n = 5). In the T-rest rats, there were higher percentages of CD4+CD8-, CD4-CD8+ and CD4-CD8- thymocytes (P < 0.05, P < 0.05 and P < 0.01 respectively) and of CD4-CD8+ splenocytes (P < 0.01), and a lower percentage of CD4-CD8+ cells in the lymph nodes (P < 0.01). Compared with T-rest or C rats, trained rats (n = 5) or untrained rats (n = 5) sacrificed immediately after a running session (60 min, 30 m.min-1) had a higher percentage of mononucleated cells CD4+CD8- in the blood (P < 0.05 and P < 0.01). Lastly, compared with C rats, rats (n = 5) sacrificed immediately after their 5th day of training (30-60 min.day-1) presented a higher total splenocyte population (P < 0.05) and greater in vitro production of T-cell growth factor (interleukin 2 + Interleukin 4) by splenocytes in response to a mitogen (P < 0.01). These results would indicate that moderate endurance training modifies the cellular composition of lymphoid organs, without impairing the in vitro functions of T-cells. |
| doi_str_mv | 10.1007/BF00243515 |
| format | Article |
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The T-cell populations were compared in sedentary rats (C, n = 5) and in rats trained for 4 weeks on a treadmill (30-60 min.day-1, 6 days.week-1, 20-30 m.min-1) and sacrificed at rest (T-rest, n = 5). In the T-rest rats, there were higher percentages of CD4+CD8-, CD4-CD8+ and CD4-CD8- thymocytes (P < 0.05, P < 0.05 and P < 0.01 respectively) and of CD4-CD8+ splenocytes (P < 0.01), and a lower percentage of CD4-CD8+ cells in the lymph nodes (P < 0.01). Compared with T-rest or C rats, trained rats (n = 5) or untrained rats (n = 5) sacrificed immediately after a running session (60 min, 30 m.min-1) had a higher percentage of mononucleated cells CD4+CD8- in the blood (P < 0.05 and P < 0.01). Lastly, compared with C rats, rats (n = 5) sacrificed immediately after their 5th day of training (30-60 min.day-1) presented a higher total splenocyte population (P < 0.05) and greater in vitro production of T-cell growth factor (interleukin 2 + Interleukin 4) by splenocytes in response to a mitogen (P < 0.01). These results would indicate that moderate endurance training modifies the cellular composition of lymphoid organs, without impairing the in vitro functions of T-cells.]]></description><identifier>ISSN: 0301-5548</identifier><identifier>ISSN: 1439-6319</identifier><identifier>EISSN: 1432-1025</identifier><identifier>EISSN: 1439-6327</identifier><identifier>DOI: 10.1007/BF00243515</identifier><identifier>PMID: 1425654</identifier><identifier>CODEN: EJAPCK</identifier><language>eng</language><publisher>Berlin: Springer</publisher><subject>AIDS/HIV ; Animals ; Biological and medical sciences ; CD4-CD8 Ratio ; Fundamental and applied biological sciences. Psychology ; Interleukin-2 - biosynthesis ; Interleukin-4 - biosynthesis ; Leukocyte Count ; Lymph Nodes - cytology ; Male ; Physical Conditioning, Animal ; Physical Exertion - physiology ; Rats ; Rats, Wistar ; Spleen - cytology ; T-Lymphocyte Subsets - cytology ; T-Lymphocytes - metabolism ; Thymus Gland - cytology ; Vertebrates: blood, hematopoietic organs, reticuloendothelial system</subject><ispartof>European Journal of Applied Physiology and Occupational Physiology, 1992-11, Vol.65 (5), p.464-468</ispartof><rights>1993 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c342t-f0c3425b70b4cd54399b921ec07308a73e7d781f28d8a8e905c93d4536d2a49c3</citedby><cites>FETCH-LOGICAL-c342t-f0c3425b70b4cd54399b921ec07308a73e7d781f28d8a8e905c93d4536d2a49c3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27901,27902</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=4512462$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/1425654$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>FERRY, A</creatorcontrib><creatorcontrib>RIEU, P</creatorcontrib><creatorcontrib>LAZIRI, F</creatorcontrib><creatorcontrib>EL HABAZI, A</creatorcontrib><creatorcontrib>LE PAGE, C</creatorcontrib><creatorcontrib>RIEU, M</creatorcontrib><title>Effect of moderate exercise on rat T-cells</title><title>European Journal of Applied Physiology and Occupational Physiology</title><addtitle>Eur J Appl Physiol Occup Physiol</addtitle><description><![CDATA[The aim of this study was a detailed examination of the effects of moderate exercise on T-cells in adult male Wistar rats. The T-cell populations were compared in sedentary rats (C, n = 5) and in rats trained for 4 weeks on a treadmill (30-60 min.day-1, 6 days.week-1, 20-30 m.min-1) and sacrificed at rest (T-rest, n = 5). In the T-rest rats, there were higher percentages of CD4+CD8-, CD4-CD8+ and CD4-CD8- thymocytes (P < 0.05, P < 0.05 and P < 0.01 respectively) and of CD4-CD8+ splenocytes (P < 0.01), and a lower percentage of CD4-CD8+ cells in the lymph nodes (P < 0.01). Compared with T-rest or C rats, trained rats (n = 5) or untrained rats (n = 5) sacrificed immediately after a running session (60 min, 30 m.min-1) had a higher percentage of mononucleated cells CD4+CD8- in the blood (P < 0.05 and P < 0.01). Lastly, compared with C rats, rats (n = 5) sacrificed immediately after their 5th day of training (30-60 min.day-1) presented a higher total splenocyte population (P < 0.05) and greater in vitro production of T-cell growth factor (interleukin 2 + Interleukin 4) by splenocytes in response to a mitogen (P < 0.01). These results would indicate that moderate endurance training modifies the cellular composition of lymphoid organs, without impairing the in vitro functions of T-cells.]]></description><subject>AIDS/HIV</subject><subject>Animals</subject><subject>Biological and medical sciences</subject><subject>CD4-CD8 Ratio</subject><subject>Fundamental and applied biological sciences. Psychology</subject><subject>Interleukin-2 - biosynthesis</subject><subject>Interleukin-4 - biosynthesis</subject><subject>Leukocyte Count</subject><subject>Lymph Nodes - cytology</subject><subject>Male</subject><subject>Physical Conditioning, Animal</subject><subject>Physical Exertion - physiology</subject><subject>Rats</subject><subject>Rats, Wistar</subject><subject>Spleen - cytology</subject><subject>T-Lymphocyte Subsets - cytology</subject><subject>T-Lymphocytes - metabolism</subject><subject>Thymus Gland - cytology</subject><subject>Vertebrates: blood, hematopoietic organs, reticuloendothelial system</subject><issn>0301-5548</issn><issn>1439-6319</issn><issn>1432-1025</issn><issn>1439-6327</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1992</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkE1LAzEQhoMotVYv3oU9iIfC6uRrkxy11A8oeKnnJZtMoLLbrckW9N-b0mKPnl6YeXiZeQi5pnBPAdTD0zMAE1xSeULGVHBWUmDylIyBAy2lFPqcXKT0mSkwXI3IiAomKynGZDoPAd1Q9KHoeo_RDljgN0a3Slj06yIPimXpsG3TJTkLtk14dcgJ-XieL2ev5eL95W32uCgdF2woA-xSNgoa4bwU3JjGMIoOFAdtFUfllaaBaa-tRgPSGe6F5JVnVhjHJ-Ru37uJ_dcW01B3q7S7wK6x36Zacabze_pfkGpVGcOrDE73oIt9ShFDvYmrzsafmkK9M1gfDWb45tC6bTr0R3SvLO9vD3ubnG1DtOss6w8TkjJRMf4LmLt0Kw</recordid><startdate>19921101</startdate><enddate>19921101</enddate><creator>FERRY, A</creator><creator>RIEU, P</creator><creator>LAZIRI, F</creator><creator>EL HABAZI, A</creator><creator>LE PAGE, C</creator><creator>RIEU, M</creator><general>Springer</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7TS</scope><scope>7X8</scope></search><sort><creationdate>19921101</creationdate><title>Effect of moderate exercise on rat T-cells</title><author>FERRY, A ; RIEU, P ; LAZIRI, F ; EL HABAZI, A ; LE PAGE, C ; RIEU, M</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c342t-f0c3425b70b4cd54399b921ec07308a73e7d781f28d8a8e905c93d4536d2a49c3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1992</creationdate><topic>AIDS/HIV</topic><topic>Animals</topic><topic>Biological and medical sciences</topic><topic>CD4-CD8 Ratio</topic><topic>Fundamental and applied biological sciences. Psychology</topic><topic>Interleukin-2 - biosynthesis</topic><topic>Interleukin-4 - biosynthesis</topic><topic>Leukocyte Count</topic><topic>Lymph Nodes - cytology</topic><topic>Male</topic><topic>Physical Conditioning, Animal</topic><topic>Physical Exertion - physiology</topic><topic>Rats</topic><topic>Rats, Wistar</topic><topic>Spleen - cytology</topic><topic>T-Lymphocyte Subsets - cytology</topic><topic>T-Lymphocytes - metabolism</topic><topic>Thymus Gland - cytology</topic><topic>Vertebrates: blood, hematopoietic organs, reticuloendothelial system</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>FERRY, A</creatorcontrib><creatorcontrib>RIEU, P</creatorcontrib><creatorcontrib>LAZIRI, F</creatorcontrib><creatorcontrib>EL HABAZI, A</creatorcontrib><creatorcontrib>LE PAGE, C</creatorcontrib><creatorcontrib>RIEU, M</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Physical Education Index</collection><collection>MEDLINE - Academic</collection><jtitle>European Journal of Applied Physiology and Occupational Physiology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>FERRY, A</au><au>RIEU, P</au><au>LAZIRI, F</au><au>EL HABAZI, A</au><au>LE PAGE, C</au><au>RIEU, M</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Effect of moderate exercise on rat T-cells</atitle><jtitle>European Journal of Applied Physiology and Occupational Physiology</jtitle><addtitle>Eur J Appl Physiol Occup Physiol</addtitle><date>1992-11-01</date><risdate>1992</risdate><volume>65</volume><issue>5</issue><spage>464</spage><epage>468</epage><pages>464-468</pages><issn>0301-5548</issn><issn>1439-6319</issn><eissn>1432-1025</eissn><eissn>1439-6327</eissn><coden>EJAPCK</coden><abstract><![CDATA[The aim of this study was a detailed examination of the effects of moderate exercise on T-cells in adult male Wistar rats. The T-cell populations were compared in sedentary rats (C, n = 5) and in rats trained for 4 weeks on a treadmill (30-60 min.day-1, 6 days.week-1, 20-30 m.min-1) and sacrificed at rest (T-rest, n = 5). In the T-rest rats, there were higher percentages of CD4+CD8-, CD4-CD8+ and CD4-CD8- thymocytes (P < 0.05, P < 0.05 and P < 0.01 respectively) and of CD4-CD8+ splenocytes (P < 0.01), and a lower percentage of CD4-CD8+ cells in the lymph nodes (P < 0.01). Compared with T-rest or C rats, trained rats (n = 5) or untrained rats (n = 5) sacrificed immediately after a running session (60 min, 30 m.min-1) had a higher percentage of mononucleated cells CD4+CD8- in the blood (P < 0.05 and P < 0.01). Lastly, compared with C rats, rats (n = 5) sacrificed immediately after their 5th day of training (30-60 min.day-1) presented a higher total splenocyte population (P < 0.05) and greater in vitro production of T-cell growth factor (interleukin 2 + Interleukin 4) by splenocytes in response to a mitogen (P < 0.01). These results would indicate that moderate endurance training modifies the cellular composition of lymphoid organs, without impairing the in vitro functions of T-cells.]]></abstract><cop>Berlin</cop><pub>Springer</pub><pmid>1425654</pmid><doi>10.1007/BF00243515</doi><tpages>5</tpages></addata></record> |
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| subjects | AIDS/HIV Animals Biological and medical sciences CD4-CD8 Ratio Fundamental and applied biological sciences. Psychology Interleukin-2 - biosynthesis Interleukin-4 - biosynthesis Leukocyte Count Lymph Nodes - cytology Male Physical Conditioning, Animal Physical Exertion - physiology Rats Rats, Wistar Spleen - cytology T-Lymphocyte Subsets - cytology T-Lymphocytes - metabolism Thymus Gland - cytology Vertebrates: blood, hematopoietic organs, reticuloendothelial system |
| title | Effect of moderate exercise on rat T-cells |
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