Modulation of the calcium pump of the kidney and testes of rats infected with Trypanosoma congolense
The activity of the CaMgATPase (Ca-pump) of the kidney and testes of Wistar rats infected with Trypanosoma congolense was studied during the course of infection. The activity of the enzyme in both organs was found to decrease with increase in parasitaemia. The transition temperature (T c) decreased...
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Veröffentlicht in: | Journal of comparative pathology 1992-07, Vol.107 (1), p.119-123 |
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container_title | Journal of comparative pathology |
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creator | Nok, A.J. Esievo, K.A.N. Ajibike, M.O. Achoba, I.I. Tekdek, K. Gimba, C.E. Kagbu, J.A. Ndams, I.S. |
description | The activity of the CaMgATPase (Ca-pump) of the kidney and testes of Wistar rats infected with
Trypanosoma congolense was studied during the course of infection. The activity of the enzyme in both organs was found to decrease with increase in parasitaemia. The transition temperature (T
c) decreased and activation energy (E
a) of the enzyme increased with increase in parasitaemia. The relevance of the Ca-pump in the pathogenesis of trypanosomiasis is discussed. |
doi_str_mv | 10.1016/0021-9975(92)90102-Z |
format | Article |
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Trypanosoma congolense was studied during the course of infection. The activity of the enzyme in both organs was found to decrease with increase in parasitaemia. The transition temperature (T
c) decreased and activation energy (E
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Trypanosoma congolense was studied during the course of infection. The activity of the enzyme in both organs was found to decrease with increase in parasitaemia. The transition temperature (T
c) decreased and activation energy (E
a) of the enzyme increased with increase in parasitaemia. The relevance of the Ca-pump in the pathogenesis of trypanosomiasis is discussed.</description><subject>adenosinetriphosphatase</subject><subject>Animals</subject><subject>Biological and medical sciences</subject><subject>Blood - parasitology</subject><subject>Ca(2+) Mg(2+)-ATPase - metabolism</subject><subject>calcium</subject><subject>Calcium-Transporting ATPases</subject><subject>enzyme activity</subject><subject>Infectious diseases</subject><subject>Kidney - enzymology</subject><subject>kidneys</subject><subject>magnesium</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Parasitic diseases</subject><subject>pathogenesis</subject><subject>Rats</subject><subject>Rats, Wistar</subject><subject>Temperature</subject><subject>testes</subject><subject>Testis - enzymology</subject><subject>Trypanosoma congolense</subject><subject>trypanosomiasis</subject><subject>Trypanosomiasis, African - enzymology</subject><subject>Trypanosomiasis, African - parasitology</subject><issn>0021-9975</issn><issn>1532-3129</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1992</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kE2L1TAUhoMo43X0HyhmIaKLaj7apNkIMvgFIy6c2cwm5CYnM9E2qUmr3H9vaq_jTggcyPucw8uD0GNKXlFCxWtCGG2Ukt0LxV4qQglrru6gHe04azhl6i7a3SL30YNSvhFC-r5jJ-iE8koQuUPuc3LLYOaQIk4ezzeArRlsWEY8LeP09-97cBEO2ESHZyj1rUE2c8EherAzOPwrzDf4Ih8mE1NJo8E2xes0QCzwEN3zZijw6DhP0eX7dxdnH5vzLx8-nb09b2xLydx0YL2SvZC8971pW-Lr5K7j3O17RQzdO0usAGOlEHZvlXWeSddSthdSGMVP0fPt7pTTj6X21GMoFobBREhL0ZIzKYhgFWw30OZUSgavpxxGkw-aEr3K1as5vZrTiuk_cvVVXXtyvL_sR3D_ljabNX92zE2pFn020YZyi7WCt1KuNZ9umDdJm-tckcuvjFBOqOz6aqASbzYCqq2fAbIuNkC04EKutrVL4f9NfwPYXKAp</recordid><startdate>19920701</startdate><enddate>19920701</enddate><creator>Nok, A.J.</creator><creator>Esievo, K.A.N.</creator><creator>Ajibike, M.O.</creator><creator>Achoba, I.I.</creator><creator>Tekdek, K.</creator><creator>Gimba, C.E.</creator><creator>Kagbu, J.A.</creator><creator>Ndams, I.S.</creator><general>Elsevier Ltd</general><general>Elsevier</general><scope>FBQ</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>19920701</creationdate><title>Modulation of the calcium pump of the kidney and testes of rats infected with Trypanosoma congolense</title><author>Nok, A.J. ; Esievo, K.A.N. ; Ajibike, M.O. ; Achoba, I.I. ; Tekdek, K. ; Gimba, C.E. ; Kagbu, J.A. ; Ndams, I.S.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c410t-5ecf9786738f8a440f8f83d533db890a1bdc0c6eac766cbc9cdf27d412b676a93</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1992</creationdate><topic>adenosinetriphosphatase</topic><topic>Animals</topic><topic>Biological and medical sciences</topic><topic>Blood - parasitology</topic><topic>Ca(2+) Mg(2+)-ATPase - metabolism</topic><topic>calcium</topic><topic>Calcium-Transporting ATPases</topic><topic>enzyme activity</topic><topic>Infectious diseases</topic><topic>Kidney - enzymology</topic><topic>kidneys</topic><topic>magnesium</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Parasitic diseases</topic><topic>pathogenesis</topic><topic>Rats</topic><topic>Rats, Wistar</topic><topic>Temperature</topic><topic>testes</topic><topic>Testis - enzymology</topic><topic>Trypanosoma congolense</topic><topic>trypanosomiasis</topic><topic>Trypanosomiasis, African - enzymology</topic><topic>Trypanosomiasis, African - parasitology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Nok, A.J.</creatorcontrib><creatorcontrib>Esievo, K.A.N.</creatorcontrib><creatorcontrib>Ajibike, M.O.</creatorcontrib><creatorcontrib>Achoba, I.I.</creatorcontrib><creatorcontrib>Tekdek, K.</creatorcontrib><creatorcontrib>Gimba, C.E.</creatorcontrib><creatorcontrib>Kagbu, J.A.</creatorcontrib><creatorcontrib>Ndams, I.S.</creatorcontrib><collection>AGRIS</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of comparative pathology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Nok, A.J.</au><au>Esievo, K.A.N.</au><au>Ajibike, M.O.</au><au>Achoba, I.I.</au><au>Tekdek, K.</au><au>Gimba, C.E.</au><au>Kagbu, J.A.</au><au>Ndams, I.S.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Modulation of the calcium pump of the kidney and testes of rats infected with Trypanosoma congolense</atitle><jtitle>Journal of comparative pathology</jtitle><addtitle>J Comp Pathol</addtitle><date>1992-07-01</date><risdate>1992</risdate><volume>107</volume><issue>1</issue><spage>119</spage><epage>123</epage><pages>119-123</pages><issn>0021-9975</issn><eissn>1532-3129</eissn><coden>JCVPAR</coden><abstract>The activity of the CaMgATPase (Ca-pump) of the kidney and testes of Wistar rats infected with
Trypanosoma congolense was studied during the course of infection. The activity of the enzyme in both organs was found to decrease with increase in parasitaemia. The transition temperature (T
c) decreased and activation energy (E
a) of the enzyme increased with increase in parasitaemia. The relevance of the Ca-pump in the pathogenesis of trypanosomiasis is discussed.</abstract><cop>London</cop><pub>Elsevier Ltd</pub><pmid>1331207</pmid><doi>10.1016/0021-9975(92)90102-Z</doi><tpages>5</tpages></addata></record> |
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subjects | adenosinetriphosphatase Animals Biological and medical sciences Blood - parasitology Ca(2+) Mg(2+)-ATPase - metabolism calcium Calcium-Transporting ATPases enzyme activity Infectious diseases Kidney - enzymology kidneys magnesium Male Medical sciences Parasitic diseases pathogenesis Rats Rats, Wistar Temperature testes Testis - enzymology Trypanosoma congolense trypanosomiasis Trypanosomiasis, African - enzymology Trypanosomiasis, African - parasitology |
title | Modulation of the calcium pump of the kidney and testes of rats infected with Trypanosoma congolense |
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