Modulation of the calcium pump of the kidney and testes of rats infected with Trypanosoma congolense

The activity of the CaMgATPase (Ca-pump) of the kidney and testes of Wistar rats infected with Trypanosoma congolense was studied during the course of infection. The activity of the enzyme in both organs was found to decrease with increase in parasitaemia. The transition temperature (T c) decreased...

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Veröffentlicht in:Journal of comparative pathology 1992-07, Vol.107 (1), p.119-123
Hauptverfasser: Nok, A.J., Esievo, K.A.N., Ajibike, M.O., Achoba, I.I., Tekdek, K., Gimba, C.E., Kagbu, J.A., Ndams, I.S.
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container_end_page 123
container_issue 1
container_start_page 119
container_title Journal of comparative pathology
container_volume 107
creator Nok, A.J.
Esievo, K.A.N.
Ajibike, M.O.
Achoba, I.I.
Tekdek, K.
Gimba, C.E.
Kagbu, J.A.
Ndams, I.S.
description The activity of the CaMgATPase (Ca-pump) of the kidney and testes of Wistar rats infected with Trypanosoma congolense was studied during the course of infection. The activity of the enzyme in both organs was found to decrease with increase in parasitaemia. The transition temperature (T c) decreased and activation energy (E a) of the enzyme increased with increase in parasitaemia. The relevance of the Ca-pump in the pathogenesis of trypanosomiasis is discussed.
doi_str_mv 10.1016/0021-9975(92)90102-Z
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The activity of the enzyme in both organs was found to decrease with increase in parasitaemia. The transition temperature (T c) decreased and activation energy (E a) of the enzyme increased with increase in parasitaemia. 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The activity of the enzyme in both organs was found to decrease with increase in parasitaemia. The transition temperature (T c) decreased and activation energy (E a) of the enzyme increased with increase in parasitaemia. The relevance of the Ca-pump in the pathogenesis of trypanosomiasis is discussed.</abstract><cop>London</cop><pub>Elsevier Ltd</pub><pmid>1331207</pmid><doi>10.1016/0021-9975(92)90102-Z</doi><tpages>5</tpages></addata></record>
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subjects adenosinetriphosphatase
Animals
Biological and medical sciences
Blood - parasitology
Ca(2+) Mg(2+)-ATPase - metabolism
calcium
Calcium-Transporting ATPases
enzyme activity
Infectious diseases
Kidney - enzymology
kidneys
magnesium
Male
Medical sciences
Parasitic diseases
pathogenesis
Rats
Rats, Wistar
Temperature
testes
Testis - enzymology
Trypanosoma congolense
trypanosomiasis
Trypanosomiasis, African - enzymology
Trypanosomiasis, African - parasitology
title Modulation of the calcium pump of the kidney and testes of rats infected with Trypanosoma congolense
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