Pharmacokinetic investigations of the α-human thrombin-hirudin complex in rhesus monkeys
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| Veröffentlicht in: | Thrombosis research 1992-05, Vol.66 (2), p.271-275 |
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| container_end_page | 275 |
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| container_issue | 2 |
| container_start_page | 271 |
| container_title | Thrombosis research |
| container_volume | 66 |
| creator | Grötsch, H. Hropot, M. Berscheid, G. Crause, P. Malerczyk, V. Apidopoulos, G. Haun, G. Husák, B. |
| description | |
| doi_str_mv | 10.1016/0049-3848(92)90198-J |
| format | Article |
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Pharmacogenetics. Drug-receptor interactions ; Pharmacology. Drug treatments ; rhesus monkeys ; Species Specificity ; Thrombin - pharmacokinetics ; Thrombin - pharmacology ; Thrombin - urine ; Thrombin Time ; thrombin-hirudin complex</subject><ispartof>Thrombosis research, 1992-05, Vol.66 (2), p.271-275</ispartof><rights>1992</rights><rights>1992 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c386t-ef57517054dd0456b44e17bf64e0730bc7b17c646c226e6ed8dda77ba3a941c83</citedby><cites>FETCH-LOGICAL-c386t-ef57517054dd0456b44e17bf64e0730bc7b17c646c226e6ed8dda77ba3a941c83</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/004938489290198J$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,776,780,3537,27901,27902,65306</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=5433146$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/1412198$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Grötsch, H.</creatorcontrib><creatorcontrib>Hropot, M.</creatorcontrib><creatorcontrib>Berscheid, G.</creatorcontrib><creatorcontrib>Crause, P.</creatorcontrib><creatorcontrib>Malerczyk, V.</creatorcontrib><creatorcontrib>Apidopoulos, G.</creatorcontrib><creatorcontrib>Haun, G.</creatorcontrib><creatorcontrib>Husák, B.</creatorcontrib><title>Pharmacokinetic investigations of the α-human thrombin-hirudin complex in rhesus monkeys</title><title>Thrombosis research</title><addtitle>Thromb Res</addtitle><subject>Amino Acid Sequence</subject><subject>Animals</subject><subject>Biological and medical sciences</subject><subject>chromogenic thrombin substrate assay</subject><subject>clotting times</subject><subject>ELISA for hirudin and THC</subject><subject>General pharmacology</subject><subject>Hirudin</subject><subject>Hirudins - pharmacokinetics</subject><subject>Hirudins - pharmacology</subject><subject>Hirudins - urine</subject><subject>Humans</subject><subject>Macaca mulatta - blood</subject><subject>Macaca mulatta - urine</subject><subject>Medical sciences</subject><subject>Metabolic Clearance Rate</subject><subject>Molecular Sequence Data</subject><subject>Partial Thromboplastin Time</subject><subject>Pharmacokinetics. Pharmacogenetics. Drug-receptor interactions</subject><subject>Pharmacology. Drug treatments</subject><subject>rhesus monkeys</subject><subject>Species Specificity</subject><subject>Thrombin - pharmacokinetics</subject><subject>Thrombin - pharmacology</subject><subject>Thrombin - urine</subject><subject>Thrombin Time</subject><subject>thrombin-hirudin complex</subject><issn>0049-3848</issn><issn>1879-2472</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1992</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kMtKxTAQhoMoery8gUIXIrqoJm2atBtBxCuCLnThKqTJ1Ebb5Ji0oo_li_hM5ngOunM1DPP9P8OH0DbBhwQTdoQxrdK8pOV-lR1UmFRler2EJqTkVZpRni2jyS-yhtZDeMaYcFIVq2iVUJLFwAQ93rXS91K5F2NhMCox9g3CYJ7kYJwNiWuSoYXk6zNtx17auHjX18amrfGjNjZRrp928B5ziW8hjCHpnX2Bj7CJVhrZBdhazA30cH52f3qZ3txeXJ2e3KQqL9mQQlPwgnBcUK0xLVhNKRBeN4wC5jmuFa8JV4wylWUMGOhSa8l5LXNZUaLKfAPtzXun3r2O8XfRm6Cg66QFNwbB84zHXhpBOgeVdyF4aMTUm176D0GwmBkVM11ipktUmfgxKq5jbGfRP9Y96L_QXGG87y7uMijZNV5aZcIvVtA8J5RF7HiOQXTxZsCLoAxYBdp4UIPQzvz_xzcBn5QO</recordid><startdate>19920501</startdate><enddate>19920501</enddate><creator>Grötsch, H.</creator><creator>Hropot, M.</creator><creator>Berscheid, G.</creator><creator>Crause, P.</creator><creator>Malerczyk, V.</creator><creator>Apidopoulos, G.</creator><creator>Haun, G.</creator><creator>Husák, B.</creator><general>Elsevier Ltd</general><general>Elsevier Science</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>19920501</creationdate><title>Pharmacokinetic investigations of the α-human thrombin-hirudin complex in rhesus monkeys</title><author>Grötsch, H. ; Hropot, M. ; Berscheid, G. ; Crause, P. ; Malerczyk, V. ; Apidopoulos, G. ; Haun, G. ; Husák, B.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c386t-ef57517054dd0456b44e17bf64e0730bc7b17c646c226e6ed8dda77ba3a941c83</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1992</creationdate><topic>Amino Acid Sequence</topic><topic>Animals</topic><topic>Biological and medical sciences</topic><topic>chromogenic thrombin substrate assay</topic><topic>clotting times</topic><topic>ELISA for hirudin and THC</topic><topic>General pharmacology</topic><topic>Hirudin</topic><topic>Hirudins - pharmacokinetics</topic><topic>Hirudins - pharmacology</topic><topic>Hirudins - urine</topic><topic>Humans</topic><topic>Macaca mulatta - blood</topic><topic>Macaca mulatta - urine</topic><topic>Medical sciences</topic><topic>Metabolic Clearance Rate</topic><topic>Molecular Sequence Data</topic><topic>Partial Thromboplastin Time</topic><topic>Pharmacokinetics. Pharmacogenetics. Drug-receptor interactions</topic><topic>Pharmacology. Drug treatments</topic><topic>rhesus monkeys</topic><topic>Species Specificity</topic><topic>Thrombin - pharmacokinetics</topic><topic>Thrombin - pharmacology</topic><topic>Thrombin - urine</topic><topic>Thrombin Time</topic><topic>thrombin-hirudin complex</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Grötsch, H.</creatorcontrib><creatorcontrib>Hropot, M.</creatorcontrib><creatorcontrib>Berscheid, G.</creatorcontrib><creatorcontrib>Crause, P.</creatorcontrib><creatorcontrib>Malerczyk, V.</creatorcontrib><creatorcontrib>Apidopoulos, G.</creatorcontrib><creatorcontrib>Haun, G.</creatorcontrib><creatorcontrib>Husák, B.</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Thrombosis research</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Grötsch, H.</au><au>Hropot, M.</au><au>Berscheid, G.</au><au>Crause, P.</au><au>Malerczyk, V.</au><au>Apidopoulos, G.</au><au>Haun, G.</au><au>Husák, B.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Pharmacokinetic investigations of the α-human thrombin-hirudin complex in rhesus monkeys</atitle><jtitle>Thrombosis research</jtitle><addtitle>Thromb Res</addtitle><date>1992-05-01</date><risdate>1992</risdate><volume>66</volume><issue>2</issue><spage>271</spage><epage>275</epage><pages>271-275</pages><issn>0049-3848</issn><eissn>1879-2472</eissn><coden>THBRAA</coden><cop>New York, NY</cop><pub>Elsevier Ltd</pub><pmid>1412198</pmid><doi>10.1016/0049-3848(92)90198-J</doi><tpages>5</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0049-3848 |
| ispartof | Thrombosis research, 1992-05, Vol.66 (2), p.271-275 |
| issn | 0049-3848 1879-2472 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_73274564 |
| source | MEDLINE; Elsevier ScienceDirect Journals |
| subjects | Amino Acid Sequence Animals Biological and medical sciences chromogenic thrombin substrate assay clotting times ELISA for hirudin and THC General pharmacology Hirudin Hirudins - pharmacokinetics Hirudins - pharmacology Hirudins - urine Humans Macaca mulatta - blood Macaca mulatta - urine Medical sciences Metabolic Clearance Rate Molecular Sequence Data Partial Thromboplastin Time Pharmacokinetics. Pharmacogenetics. Drug-receptor interactions Pharmacology. Drug treatments rhesus monkeys Species Specificity Thrombin - pharmacokinetics Thrombin - pharmacology Thrombin - urine Thrombin Time thrombin-hirudin complex |
| title | Pharmacokinetic investigations of the α-human thrombin-hirudin complex in rhesus monkeys |
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