Alteration of Polysaccharide Size Distribution of a Vertebrate Hyaluronan Synthase by Mutation

Hyaluronan (HA) is a nonsulfated glycosaminoglycan that has long been known to play structural roles in vertebrates. Recently, it has become increasingly obvious that this linear polysaccharide has many more uses than simply scaffolding or space filler. HA has been found to be involved in developmen...

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Veröffentlicht in:	The Journal of biological chemistry 2003-05, Vol.278 (22), p.19808-19814
Hauptverfasser:	Pummill, Philip E., DeAngelis, Paul L.
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Chromatography, Gel Electrophoresis, Agar Gel Glucuronosyltransferase - chemistry Glucuronosyltransferase - isolation & purification Glucuronosyltransferase - metabolism Glycosyltransferases Hyaluronan Synthases Kinetics Membrane Proteins Molecular Sequence Data Polysaccharides - chemistry Sequence Homology, Amino Acid Transferases Xenopus Proteins
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