The bacterial universal stress protein: function and regulation

The universal stress protein A (UspA) superfamily encompasses an ancient and conserved group of proteins that are found in bacteria, Archea, fungi, flies and plants. The Escherichia coli UspA is produced in response to a large number of different environmental onslaughts and UspA is one of the most...

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Veröffentlicht in:Current opinion in microbiology 2003-04, Vol.6 (2), p.140-145
Hauptverfasser: Kvint, Kristian, Nachin, Laurence, Diez, Alfredo, Nyström, Thomas
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container_issue 2
container_start_page 140
container_title Current opinion in microbiology
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creator Kvint, Kristian
Nachin, Laurence
Diez, Alfredo
Nyström, Thomas
description The universal stress protein A (UspA) superfamily encompasses an ancient and conserved group of proteins that are found in bacteria, Archea, fungi, flies and plants. The Escherichia coli UspA is produced in response to a large number of different environmental onslaughts and UspA is one of the most abundant proteins in growth-arrested cells. Although insights into the regulation of the E. coli uspA gene have been gained, the exact roles of the Usp proteins and Usp domains remain enigmatic; they appear, in some cases, to be linked to resistance to DNA-damaging agents and to respiratory uncouplers.
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subjects Bacterial Proteins - biosynthesis
Bacterial Proteins - chemistry
Bacterial Proteins - genetics
Bacterial Proteins - physiology
Biological Factors - classification
Biological Factors - metabolism
Escherichia coli - genetics
Escherichia coli - metabolism
Escherichia coli Proteins - biosynthesis
Escherichia coli Proteins - chemistry
Escherichia coli Proteins - genetics
Escherichia coli Proteins - physiology
Gene Expression Regulation, Bacterial
Heat-Shock Proteins - biosynthesis
Heat-Shock Proteins - chemistry
Heat-Shock Proteins - genetics
Heat-Shock Proteins - physiology
Models, Genetic
title The bacterial universal stress protein: function and regulation
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