Dissociation of T helper type 2 cytokine-dependent airway lesions from signal transducer and activator of transcription 6 signalling in experimental chronic asthma

Summary Background Type 2 T helper lymphocytes (Th2 cells) and their cytokine products are important in the pathogenesis of asthma. Objective To examine the contribution of the signal transducer and activator of transcription (STAT) 6 pathway, involved in Th2 cytokine signalling, to the development...

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