Improvement of the GenTHREADER method for genomic fold recognition

Motivation: In order to enhance genome annotation, the fully automatic fold recognition method GenTHREADER has been improved and benchmarked. The previous version of GenTHREADER consisted of a simple neural network which was trained to combine sequence alignment score, length information and energy...

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Veröffentlicht in:	Bioinformatics 2003-05, Vol.19 (7), p.874-881
Hauptverfasser:	McGuffin, Liam J., Jones, David T.
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Animals Biological and medical sciences Databases, Protein False Positive Reactions Fundamental and applied biological sciences. Psychology General aspects Genome Mathematics in biology. Statistical analysis. Models. Metrology. Data processing in biology (general aspects) Molecular Sequence Data Protein Folding Protein Structure, Secondary Proteins - chemistry Proteins - classification Quality Control Reproducibility of Results Sensitivity and Specificity Sequence Alignment - methods Sequence Alignment - standards Sequence Analysis, Protein Sequence Homology Software
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