Ribonucleotide reductase: regulation, regulation, regulation

Ribonucleotide reductase (RNR) catalyses the rate limiting step in the production of deoxyribonucleotides needed for DNA synthesis. It is composed of two dissimilar subunits, R1, the large subunit containing the allosteric regulatory sites, and R2, the small subunit containing a binuclear iron cente...

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Veröffentlicht in:	Trends in biochemical sciences (Amsterdam. Regular ed.) 1992-03, Vol.17 (3), p.119-123
Hauptverfasser:	Elledge, Stephen J., Zhou, Zheng, Allen, James B.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Base Sequence Cell Cycle - genetics DNA Damage - genetics DNA repair DNA Replication enzymatic activity Gene Expression Regulation, Enzymologic Molecular Sequence Data regulation reviews ribonucleoside-diphosphate reductase Ribonucleotide Reductases - genetics RNA, Messenger - genetics Saccharomyces cerevisiae - genetics transcription Transcription, Genetic
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