Rat cerebral endothelial cells express trk C and are regulated by neurotrophin-3

Cerebral endothelial cells (CEC) are critical for formation of the vascular system in the mammalian central nervous system (CNS). We focused on the neurotrophin (NT) for its possible involvement in signaling for the regulation of CEC to control formation and maintenance of the vascular system in CNS...

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Veröffentlicht in:	Biochemical and biophysical research communications 2003-05, Vol.305 (2), p.400-406
Hauptverfasser:	Takeo, Chikari, Nakamura, Susumu, Tanaka, Tomoaki, Uchida, Daigaku, Noguchi, Yoshihiko, Nagao, Toshitaka, Saito, Yasushi, Tatsuno, Ichiro
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Aorta - cytology Cell Culture Techniques Cell Division - drug effects Cells, Cultured Cerebral Cortex - cytology Cerebral endothelial cells Endothelium, Vascular - cytology Endothelium, Vascular - drug effects Endothelium, Vascular - metabolism Gene Expression Regulation Male Nerve Growth Factors - pharmacology Neurotrophin Neurotrophin 3 - pharmacology Nitric oxide Nitric Oxide - biosynthesis Nitric Oxide Synthase - metabolism Nitric Oxide Synthase Type III Proliferation Rats Rats, Wistar Receptor, trkC - biosynthesis Receptor, trkC - genetics Receptors, Nerve Growth Factor - biosynthesis Receptors, Nerve Growth Factor - genetics RNA, Messenger - biosynthesis Trk
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