Drug and Vehicle Deposition from Topical Applications: Use of In Vitro Mass Balance Technique with Minoxidil Solutions

The disposition of minoxidil and propylene glycol from topical solutions was measured by using an in vitro mass balance technique. The experimental approach included assessment of the following compartments of the skin and the diffusion cell as a function of time: (1) donor compartment; (2) hairless...

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Veröffentlicht in:Journal of pharmaceutical sciences 1992-08, Vol.81 (8), p.736-743
Hauptverfasser: Tsai, Jui-Chen, Flynn, Gordon L., Weiner, Norman D., Cappel, Markus J., Kreuter, Jörg, Ferry, James J.
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Sprache:eng
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