Direct measurement of glucose gradients and mass transport within islets of Langerhans

A glucose oxidase-based glucose microsensor (70 mm Hg. Spatially resolved glucose measurements revealed a glucose gradient around and inside single islets. From measurement of the glucose gradient, a glucose consumption rate of 0.48±0.14 pmol/nL islet/min ( n=6) and an intraislet glucose diffusion c...

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Veröffentlicht in:	Biochemical and biophysical research communications 2003-05, Vol.304 (2), p.371-377
Hauptverfasser:	Kauri, Lisa M, Jung, Sung-Kwon, Kennedy, Robert T
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological Transport Biosensing Techniques Cells, Cultured Glucokinase Glucose - analysis Glucose - metabolism Glucose consumption Glucose Oxidase - metabolism Glucose sensor Glucose transport Islets of Langerhans - chemistry Islets of Langerhans - metabolism Kinetics Mice Microelectrodes Pancreatic islet
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