Ghrelin Arg51Gln mutation is a risk factor for Type 2 diabetes and hypertension in a random sample of middle-aged subjects

Experimental studies have suggested that ghrelin, a novel gastrointestinal peptide hormone, could play a role in glucose homeostasis. In addition, ghrelin has been associated with beneficial haemodynamic effects in experimental settings. Since the Arg51Gln mutation changes the carboxyterminal amino...

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Veröffentlicht in:	Diabetologia 2003-04, Vol.46 (4), p.455-458
Hauptverfasser:	PÖYKKÖ, S, UKKOLA, O, KAUMA, H, SAVOLAINEN, M. J, KESÄNIEMI, Y. A
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Substitution - genetics Biological and medical sciences Diabetes Mellitus, Type 2 - complications Diabetes Mellitus, Type 2 - epidemiology Diabetes Mellitus, Type 2 - genetics Diabetic Angiopathies - epidemiology Diabetic Angiopathies - genetics Female Fundamental and applied biological sciences. Psychology Ghrelin Glucose Tolerance Test Humans Insulin-Like Growth Factor I - chemistry Insulin-Like Growth Factor I - genetics Male Middle Aged Mutation Peptide Hormones - genetics Random Allocation Risk Factors
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