Apoptosis repressor with caspase domain inhibits cardiomyocyte apoptosis by reducing K+ currents

Department of Medicine, School of Medicine, University of California, San Diego, California 92103 Cell shrinkage is an early prerequisite in programmed cell death, and cytoplasmic K + is a dominant cation that controls intracellular ion homeostasis and cell volume. Blockade of K + channels inhibits...

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Veröffentlicht in:	American Journal of Physiology: Cell Physiology 2003-06, Vol.284 (6), p.C1405-C1410
Hauptverfasser:	Ekhterae, Daryoush, Platoshyn, Oleksandr, Zhang, Shen, Remillard, Carmelle V, Yuan, Jason X.-J
Format:	Artikel
Sprache:	eng
Schlagworte:	4-Aminopyridine - pharmacology Animals Apoptosis - physiology Apoptosis Regulatory Proteins Cell Line Enzyme Inhibitors - pharmacology Humans Muscle Proteins - genetics Muscle Proteins - metabolism Myocytes, Cardiac - cytology Myocytes, Cardiac - drug effects Myocytes, Cardiac - physiology Patch-Clamp Techniques Potassium - metabolism Potassium Channel Blockers - pharmacology Potassium Channels, Voltage-Gated - metabolism Rats Staurosporine - pharmacology
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