Enhancement of antibacterial and lipopolysaccharide binding activities of a human lactoferrin peptide fragment by the addition of acyl chain

Cationic antibacterial peptides are potentially therapeutic in the treatment of sepsis, because of their amalgamated antibacterial and lipopolysaccharide-binding activities. We prepared acyl analogues of the peptide fragment of human lactoferrin, which originally had weak antibacterial activity. It...

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Veröffentlicht in:Journal of antimicrobial chemotherapy 2003-05, Vol.51 (5), p.1159-1165
Hauptverfasser: Majerle, Andreja, Kidrič, Jurka, Jerala, Roman
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Sprache:eng
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