Development of real time PCR assays for the quantification of Fas and FasL mRNA levels in lymphocytes: studies on centenarians

Apoptosis plays a central role in the homeostasis of the immune system. During aging, there is an altered regulation of pivotal molecules that are responsible for the regulation of this type of cell death, such as those of the Fas/FasL system. Understanding the regulation of these genes can help to...

Ausführliche Beschreibung