A comparative structural characterization of the human NSCL-1 and NSCL-2 genes. Two basic helix-loop-helix genes expressed in the developing nervous system

Human cDNA clones for NSCL-1 and NSCL-2, two basic domain helix-loop-helix (bHLH) genes expressed predominantly in the developing nervous system, were obtained from a fetal brain cDNA library. The full-length transcripts and the genomic structures were determined. The cDNAs for the two genes encode...

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Veröffentlicht in:	The Journal of biological chemistry 1992-10, Vol.267 (29), p.21065-21071
Hauptverfasser:	Lipkowitz, S, Göbel, V, Varterasian, M L, Nakahara, K, Tchorz, K, Kirsch, I R
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Animals Base Sequence Basic Helix-Loop-Helix Transcription Factors brain Brain - embryology Brain - physiology Brain Neoplasms Carcinoma, Non-Small-Cell Lung Carcinoma, Small Cell cDNA Codon DNA - genetics DNA - isolation & purification DNA-Binding Proteins - genetics expression Fetus Gene Expression gene products genes Genomic Library helix-loop-helix proteins Humans Lung Neoplasms man Mice Molecular Sequence Data Neuroblastoma NSCL-1 gene NSCL-2 gene nucleotide sequence predictions Regulatory Sequences, Nucleic Acid Restriction Mapping Sequence Homology, Amino Acid Transcription, Genetic Tumor Cells, Cultured
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