Polymorphic markers in the 5alpha-reductase type II gene and the incidence of prostate cancer

In the prostate, the enzyme encoded by the SRD5A2 gene (5alpha-reductase) converts testosterone to dihydrotestosterone, a potent androgen that has been hypothesized to play a role in the genesis of prostate cancer. Several polymorphisms have been identified in the SRD5A2 gene, including a valine-to-...

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Veröffentlicht in:	International journal of cancer 2003-07, Vol.105 (4), p.480-483
Hauptverfasser:	Lamharzi, Najib, Johnson, Melissa M, Goodman, Gary, Etzioni, Ruth, Weiss, Noel S, Dightman, Douglas A, Barnett, Matt, DiTommaso, Dante, Chen, Chu
Format:	Artikel
Sprache:	eng
Schlagworte:	3-Oxo-5-alpha-Steroid 4-Dehydrogenase - genetics Case-Control Studies Gene Frequency Humans Male Middle Aged Polymorphism, Genetic Prostatic Neoplasms - epidemiology Prostatic Neoplasms - genetics Risk
Online-Zugang:	Volltext
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