Cryptococcal meningitis in systemic lupus erythematosus
Two cases of cryptococcal meningitis occurring in patients with systemic lupus erythematosus (SLE) are presented, and 24 additional cases from the literature are reviewed. The insidious onset of this infrequent complication is emphasized. The nonspecific neurological findings associated with this in...
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| Veröffentlicht in: | Seminars in arthritis and rheumatism 1992-08, Vol.22 (1), p.18-24 |
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| container_title | Seminars in arthritis and rheumatism |
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| creator | Zimmermann, Bernard Spiegel, Michael Lally, Edward V. |
| description | Two cases of cryptococcal meningitis occurring in patients with systemic lupus erythematosus (SLE) are presented, and 24 additional cases from the literature are reviewed. The insidious onset of this infrequent complication is emphasized. The nonspecific neurological findings associated with this infection are often mistakenly diagnosed as a central nervous system manifestation of SLE. Earlier diagnosis and effective antifungal therapy have improved the prognosis of cryptococcal meningitis in SLE patients in recent years. Strategies for the treatment of patients with this complication are discussed. |
| doi_str_mv | 10.1016/0049-0172(92)90044-E |
| format | Article |
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The insidious onset of this infrequent complication is emphasized. The nonspecific neurological findings associated with this infection are often mistakenly diagnosed as a central nervous system manifestation of SLE. Earlier diagnosis and effective antifungal therapy have improved the prognosis of cryptococcal meningitis in SLE patients in recent years. Strategies for the treatment of patients with this complication are discussed.</description><identifier>ISSN: 0049-0172</identifier><identifier>EISSN: 1532-866X</identifier><identifier>DOI: 10.1016/0049-0172(92)90044-E</identifier><identifier>PMID: 1411578</identifier><identifier>CODEN: SAHRBF</identifier><language>eng</language><publisher>Philadelphia, PA: Elsevier Inc</publisher><subject>Adult ; Amphotericin B - therapeutic use ; Biological and medical sciences ; Cryptococcus - isolation & purification ; Female ; Flucytosine - therapeutic use ; Humans ; Lupus Erythematosus, Systemic - complications ; Medical sciences ; Meningitis, Cryptococcal - cerebrospinal fluid ; Meningitis, Cryptococcal - complications ; Meningitis, Cryptococcal - drug therapy ; Prednisone - therapeutic use ; Sarcoidosis. Granulomatous diseases of unproved etiology. Connective tissue diseases. Elastic tissue diseases. 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The insidious onset of this infrequent complication is emphasized. The nonspecific neurological findings associated with this infection are often mistakenly diagnosed as a central nervous system manifestation of SLE. Earlier diagnosis and effective antifungal therapy have improved the prognosis of cryptococcal meningitis in SLE patients in recent years. Strategies for the treatment of patients with this complication are discussed.</description><subject>Adult</subject><subject>Amphotericin B - therapeutic use</subject><subject>Biological and medical sciences</subject><subject>Cryptococcus - isolation & purification</subject><subject>Female</subject><subject>Flucytosine - therapeutic use</subject><subject>Humans</subject><subject>Lupus Erythematosus, Systemic - complications</subject><subject>Medical sciences</subject><subject>Meningitis, Cryptococcal - cerebrospinal fluid</subject><subject>Meningitis, Cryptococcal - complications</subject><subject>Meningitis, Cryptococcal - drug therapy</subject><subject>Prednisone - therapeutic use</subject><subject>Sarcoidosis. Granulomatous diseases of unproved etiology. Connective tissue diseases. Elastic tissue diseases. 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Granulomatous diseases of unproved etiology. Connective tissue diseases. Elastic tissue diseases. Vasculitis</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Zimmermann, Bernard</creatorcontrib><creatorcontrib>Spiegel, Michael</creatorcontrib><creatorcontrib>Lally, Edward V.</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Seminars in arthritis and rheumatism</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Zimmermann, Bernard</au><au>Spiegel, Michael</au><au>Lally, Edward V.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Cryptococcal meningitis in systemic lupus erythematosus</atitle><jtitle>Seminars in arthritis and rheumatism</jtitle><addtitle>Semin Arthritis Rheum</addtitle><date>1992-08-01</date><risdate>1992</risdate><volume>22</volume><issue>1</issue><spage>18</spage><epage>24</epage><pages>18-24</pages><issn>0049-0172</issn><eissn>1532-866X</eissn><coden>SAHRBF</coden><abstract>Two cases of cryptococcal meningitis occurring in patients with systemic lupus erythematosus (SLE) are presented, and 24 additional cases from the literature are reviewed. The insidious onset of this infrequent complication is emphasized. The nonspecific neurological findings associated with this infection are often mistakenly diagnosed as a central nervous system manifestation of SLE. Earlier diagnosis and effective antifungal therapy have improved the prognosis of cryptococcal meningitis in SLE patients in recent years. Strategies for the treatment of patients with this complication are discussed.</abstract><cop>Philadelphia, PA</cop><pub>Elsevier Inc</pub><pmid>1411578</pmid><doi>10.1016/0049-0172(92)90044-E</doi><tpages>7</tpages></addata></record> |
| fulltext | fulltext |
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| ispartof | Seminars in arthritis and rheumatism, 1992-08, Vol.22 (1), p.18-24 |
| issn | 0049-0172 1532-866X |
| language | eng |
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| source | MEDLINE; Elsevier ScienceDirect Journals Complete |
| subjects | Adult Amphotericin B - therapeutic use Biological and medical sciences Cryptococcus - isolation & purification Female Flucytosine - therapeutic use Humans Lupus Erythematosus, Systemic - complications Medical sciences Meningitis, Cryptococcal - cerebrospinal fluid Meningitis, Cryptococcal - complications Meningitis, Cryptococcal - drug therapy Prednisone - therapeutic use Sarcoidosis. Granulomatous diseases of unproved etiology. Connective tissue diseases. Elastic tissue diseases. Vasculitis |
| title | Cryptococcal meningitis in systemic lupus erythematosus |
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