Depersonalisation disorder: clinical features of 204 cases
Depersonalisation disorder is a poorly understood and underresearched syndrome. To carry out a large and comprehensive clinical and psychopathological survey of a series of patients who made contact with a research clinic. A total of 204 consecutive eligible referrals were included: 124 had a full p...
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Veröffentlicht in: | British journal of psychiatry 2003-05, Vol.182 (5), p.428-433 |
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container_title | British journal of psychiatry |
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creator | Baker, Dawn Hunter, Elaine Lawrence, Emma Medford, Nicholas Patel, Maxine Senior, Carl Sierra, Mauricio Lambert, Michelle V. Phillips, Mary L. David, Anthony S. |
description | Depersonalisation disorder is a poorly understood and underresearched syndrome.
To carry out a large and comprehensive clinical and psychopathological survey of a series of patients who made contact with a research clinic.
A total of 204 consecutive eligible referrals were included: 124 had a full psychiatric examination using items of the Present State Examination to define depersonalisation/derealisation and 80 had either a telephone interview (n=22) or filled out a number of self-report questionnaires. Cases assessed were diagnosed according to DSM-IV criteria.
The mean age of onset was 22.8 years; early onset was associated with greater severity. There was a slight male preponderance. The disorder tended to be chronic and persistent. Seventy-one per cent met DSM-IV criteria for primary depersonalisation disorder. Depersonalisation symptom scores correlated with both anxiety and depression and a past history of these disorders was commonly reported. 'Dissociative amnesia' was not prominent.
Depersonalisation disorder is a recognisable clinical entity but appears to have significant comorbidity with anxiety and depression. Research into its aetiology and treatment is warranted. |
doi_str_mv | 10.1192/bjp.182.5.428 |
format | Article |
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To carry out a large and comprehensive clinical and psychopathological survey of a series of patients who made contact with a research clinic.
A total of 204 consecutive eligible referrals were included: 124 had a full psychiatric examination using items of the Present State Examination to define depersonalisation/derealisation and 80 had either a telephone interview (n=22) or filled out a number of self-report questionnaires. Cases assessed were diagnosed according to DSM-IV criteria.
The mean age of onset was 22.8 years; early onset was associated with greater severity. There was a slight male preponderance. The disorder tended to be chronic and persistent. Seventy-one per cent met DSM-IV criteria for primary depersonalisation disorder. Depersonalisation symptom scores correlated with both anxiety and depression and a past history of these disorders was commonly reported. 'Dissociative amnesia' was not prominent.
Depersonalisation disorder is a recognisable clinical entity but appears to have significant comorbidity with anxiety and depression. Research into its aetiology and treatment is warranted.</description><identifier>ISSN: 0007-1250</identifier><identifier>EISSN: 1472-1465</identifier><identifier>DOI: 10.1192/bjp.182.5.428</identifier><identifier>PMID: 12724246</identifier><language>eng</language><publisher>Cambridge, UK: Cambridge University Press</publisher><subject>Adolescent ; Adult ; Age ; Age of Onset ; Aged ; Amnesia ; Analysis of Variance ; Anxiety ; Anxiety - epidemiology ; Child ; Child, Preschool ; Chronic Disease ; Cohort Studies ; Comorbidity ; Depersonalization ; Depersonalization - epidemiology ; Depersonalization - etiology ; Depersonalization - psychology ; Depression - epidemiology ; Diagnosis, Differential ; Dissociative amnesia ; Divorce ; Etiology ; Female ; Females ; Humans ; Male ; Males ; Medical referrals ; Mental depression ; Middle Aged ; Psychiatric Status Rating Scales ; Psychiatry ; Questionnaires ; Risk Factors ; Self report</subject><ispartof>British journal of psychiatry, 2003-05, Vol.182 (5), p.428-433</ispartof><rights>Copyright © 2003 The Royal College of Psychiatrists</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c422t-2188263f78f8df6988f855a540c1b2f3a5071b1a5be89022e7316f6a08bc24e63</citedby><cites>FETCH-LOGICAL-c422t-2188263f78f8df6988f855a540c1b2f3a5071b1a5be89022e7316f6a08bc24e63</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.cambridge.org/core/product/identifier/S0007125000228675/type/journal_article$$EHTML$$P50$$Gcambridge$$H</linktohtml><link.rule.ids>164,314,776,780,12825,27901,27902,30976,55603</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/12724246$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Baker, Dawn</creatorcontrib><creatorcontrib>Hunter, Elaine</creatorcontrib><creatorcontrib>Lawrence, Emma</creatorcontrib><creatorcontrib>Medford, Nicholas</creatorcontrib><creatorcontrib>Patel, Maxine</creatorcontrib><creatorcontrib>Senior, Carl</creatorcontrib><creatorcontrib>Sierra, Mauricio</creatorcontrib><creatorcontrib>Lambert, Michelle V.</creatorcontrib><creatorcontrib>Phillips, Mary L.</creatorcontrib><creatorcontrib>David, Anthony S.</creatorcontrib><title>Depersonalisation disorder: clinical features of 204 cases</title><title>British journal of psychiatry</title><addtitle>Br J Psychiatry</addtitle><description>Depersonalisation disorder is a poorly understood and underresearched syndrome.
To carry out a large and comprehensive clinical and psychopathological survey of a series of patients who made contact with a research clinic.
A total of 204 consecutive eligible referrals were included: 124 had a full psychiatric examination using items of the Present State Examination to define depersonalisation/derealisation and 80 had either a telephone interview (n=22) or filled out a number of self-report questionnaires. Cases assessed were diagnosed according to DSM-IV criteria.
The mean age of onset was 22.8 years; early onset was associated with greater severity. There was a slight male preponderance. The disorder tended to be chronic and persistent. Seventy-one per cent met DSM-IV criteria for primary depersonalisation disorder. Depersonalisation symptom scores correlated with both anxiety and depression and a past history of these disorders was commonly reported. 'Dissociative amnesia' was not prominent.
Depersonalisation disorder is a recognisable clinical entity but appears to have significant comorbidity with anxiety and depression. Research into its aetiology and treatment is warranted.</description><subject>Adolescent</subject><subject>Adult</subject><subject>Age</subject><subject>Age of Onset</subject><subject>Aged</subject><subject>Amnesia</subject><subject>Analysis of Variance</subject><subject>Anxiety</subject><subject>Anxiety - epidemiology</subject><subject>Child</subject><subject>Child, Preschool</subject><subject>Chronic Disease</subject><subject>Cohort Studies</subject><subject>Comorbidity</subject><subject>Depersonalization</subject><subject>Depersonalization - epidemiology</subject><subject>Depersonalization - etiology</subject><subject>Depersonalization - psychology</subject><subject>Depression - epidemiology</subject><subject>Diagnosis, Differential</subject><subject>Dissociative amnesia</subject><subject>Divorce</subject><subject>Etiology</subject><subject>Female</subject><subject>Females</subject><subject>Humans</subject><subject>Male</subject><subject>Males</subject><subject>Medical referrals</subject><subject>Mental depression</subject><subject>Middle Aged</subject><subject>Psychiatric Status Rating Scales</subject><subject>Psychiatry</subject><subject>Questionnaires</subject><subject>Risk Factors</subject><subject>Self report</subject><issn>0007-1250</issn><issn>1472-1465</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2003</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>7QJ</sourceid><sourceid>8G5</sourceid><sourceid>BENPR</sourceid><sourceid>GUQSH</sourceid><sourceid>M2O</sourceid><recordid>eNptkE1LLDEQRYMoOk9dupUW4e16TFUnnYw78eMpCG50HdLpipOhZ7pNphH_vZEZEOWtioLDvVWHsRPgU4AZXjSLYQoap3IqUO-wCQiFJYha7rIJ51yVgJIfsD8pLfJaCVT77ABQoUBRT9jlDQ0UU7-yXUh2HfpV0YbUx5biZeG6sArOdoUnux4jpaL3BXJROJsoHbE9b7tEx9t5yF7ubp-v78vHp38P11ePpROI6xJBa6wrr7TXra9nOk8prRTcQYO-spIraMDKhvSMI5KqoPa15bpxKKiuDtnfTe4Q-7eR0tosQ3LUdXZF_ZiMqlCAVlUGz3-Bi36M-bNksAJZc0DkmSo3lIt9SpG8GWJY2vhhgJsvpSYrNVmpkSYrzfzpNnVsltR-01uHGTjbAPPwOn8PkUx0Q_pw8x8hF9tSu2xiaF_p-7b_134CRKiJ3g</recordid><startdate>200305</startdate><enddate>200305</enddate><creator>Baker, Dawn</creator><creator>Hunter, Elaine</creator><creator>Lawrence, Emma</creator><creator>Medford, Nicholas</creator><creator>Patel, Maxine</creator><creator>Senior, Carl</creator><creator>Sierra, Mauricio</creator><creator>Lambert, Michelle V.</creator><creator>Phillips, Mary L.</creator><creator>David, Anthony S.</creator><general>Cambridge University Press</general><general>RCP</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>0-V</scope><scope>3V.</scope><scope>7QJ</scope><scope>7TK</scope><scope>7XB</scope><scope>88G</scope><scope>88J</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>8G5</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>ALSLI</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>GUQSH</scope><scope>HEHIP</scope><scope>M2M</scope><scope>M2O</scope><scope>M2R</scope><scope>M2S</scope><scope>MBDVC</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>PSYQQ</scope><scope>Q9U</scope><scope>7X8</scope></search><sort><creationdate>200305</creationdate><title>Depersonalisation disorder: clinical features of 204 cases</title><author>Baker, Dawn ; Hunter, Elaine ; Lawrence, Emma ; Medford, Nicholas ; Patel, Maxine ; Senior, Carl ; Sierra, Mauricio ; Lambert, Michelle V. ; Phillips, Mary L. ; David, Anthony S.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c422t-2188263f78f8df6988f855a540c1b2f3a5071b1a5be89022e7316f6a08bc24e63</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2003</creationdate><topic>Adolescent</topic><topic>Adult</topic><topic>Age</topic><topic>Age of Onset</topic><topic>Aged</topic><topic>Amnesia</topic><topic>Analysis of Variance</topic><topic>Anxiety</topic><topic>Anxiety - epidemiology</topic><topic>Child</topic><topic>Child, Preschool</topic><topic>Chronic Disease</topic><topic>Cohort Studies</topic><topic>Comorbidity</topic><topic>Depersonalization</topic><topic>Depersonalization - epidemiology</topic><topic>Depersonalization - etiology</topic><topic>Depersonalization - psychology</topic><topic>Depression - epidemiology</topic><topic>Diagnosis, Differential</topic><topic>Dissociative amnesia</topic><topic>Divorce</topic><topic>Etiology</topic><topic>Female</topic><topic>Females</topic><topic>Humans</topic><topic>Male</topic><topic>Males</topic><topic>Medical referrals</topic><topic>Mental depression</topic><topic>Middle Aged</topic><topic>Psychiatric Status Rating Scales</topic><topic>Psychiatry</topic><topic>Questionnaires</topic><topic>Risk Factors</topic><topic>Self report</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Baker, Dawn</creatorcontrib><creatorcontrib>Hunter, Elaine</creatorcontrib><creatorcontrib>Lawrence, Emma</creatorcontrib><creatorcontrib>Medford, Nicholas</creatorcontrib><creatorcontrib>Patel, Maxine</creatorcontrib><creatorcontrib>Senior, Carl</creatorcontrib><creatorcontrib>Sierra, Mauricio</creatorcontrib><creatorcontrib>Lambert, Michelle V.</creatorcontrib><creatorcontrib>Phillips, Mary L.</creatorcontrib><creatorcontrib>David, Anthony S.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Social Sciences Premium Collection</collection><collection>ProQuest Central (Corporate)</collection><collection>Applied Social Sciences Index & Abstracts (ASSIA)</collection><collection>Neurosciences Abstracts</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Psychology Database (Alumni)</collection><collection>Social Science Database (Alumni Edition)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Research Library (Alumni Edition)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>Social Science Premium Collection</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>Research Library Prep</collection><collection>Sociology Collection</collection><collection>Psychology Database</collection><collection>Research Library</collection><collection>Social Science Database</collection><collection>Sociology Database</collection><collection>Research Library (Corporate)</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>ProQuest One Psychology</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><jtitle>British journal of psychiatry</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Baker, Dawn</au><au>Hunter, Elaine</au><au>Lawrence, Emma</au><au>Medford, Nicholas</au><au>Patel, Maxine</au><au>Senior, Carl</au><au>Sierra, Mauricio</au><au>Lambert, Michelle V.</au><au>Phillips, Mary L.</au><au>David, Anthony S.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Depersonalisation disorder: clinical features of 204 cases</atitle><jtitle>British journal of psychiatry</jtitle><addtitle>Br J Psychiatry</addtitle><date>2003-05</date><risdate>2003</risdate><volume>182</volume><issue>5</issue><spage>428</spage><epage>433</epage><pages>428-433</pages><issn>0007-1250</issn><eissn>1472-1465</eissn><abstract>Depersonalisation disorder is a poorly understood and underresearched syndrome.
To carry out a large and comprehensive clinical and psychopathological survey of a series of patients who made contact with a research clinic.
A total of 204 consecutive eligible referrals were included: 124 had a full psychiatric examination using items of the Present State Examination to define depersonalisation/derealisation and 80 had either a telephone interview (n=22) or filled out a number of self-report questionnaires. Cases assessed were diagnosed according to DSM-IV criteria.
The mean age of onset was 22.8 years; early onset was associated with greater severity. There was a slight male preponderance. The disorder tended to be chronic and persistent. Seventy-one per cent met DSM-IV criteria for primary depersonalisation disorder. Depersonalisation symptom scores correlated with both anxiety and depression and a past history of these disorders was commonly reported. 'Dissociative amnesia' was not prominent.
Depersonalisation disorder is a recognisable clinical entity but appears to have significant comorbidity with anxiety and depression. Research into its aetiology and treatment is warranted.</abstract><cop>Cambridge, UK</cop><pub>Cambridge University Press</pub><pmid>12724246</pmid><doi>10.1192/bjp.182.5.428</doi><tpages>6</tpages><oa>free_for_read</oa></addata></record> |
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source | Applied Social Sciences Index & Abstracts (ASSIA); MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; Alma/SFX Local Collection; Cambridge University Press Journals Complete |
subjects | Adolescent Adult Age Age of Onset Aged Amnesia Analysis of Variance Anxiety Anxiety - epidemiology Child Child, Preschool Chronic Disease Cohort Studies Comorbidity Depersonalization Depersonalization - epidemiology Depersonalization - etiology Depersonalization - psychology Depression - epidemiology Diagnosis, Differential Dissociative amnesia Divorce Etiology Female Females Humans Male Males Medical referrals Mental depression Middle Aged Psychiatric Status Rating Scales Psychiatry Questionnaires Risk Factors Self report |
title | Depersonalisation disorder: clinical features of 204 cases |
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