The role of the endothelium in severe sepsis and multiple organ dysfunction syndrome

Severe sepsis, defined as sepsis with acute organ dysfunction, is associated with high morbidity and mortality rates. The development of novel therapies for sepsis is critically dependent on an understanding of the basic mechanisms of the disease. The pathophysiology of severe sepsis involves a high...

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Veröffentlicht in:	Blood 2003-05, Vol.101 (10), p.3765-3777
1. Verfasser:	Aird, William C.
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Endothelium, Vascular - physiopathology Fundamental and applied biological sciences. Psychology General aspects Humans Inflammation Microbiology Molecular and cellular biology Multiple Organ Failure - physiopathology Sepsis - physiopathology Sepsis - therapy
Online-Zugang:	Volltext
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