Macrophage response to cross-linked and conventional UHMWPE

To prevent wear debris-induced osteolysis and aseptic loosening, cross-linked ultra-high molecular weight polyethylene's (UHMWPE) with improved wear resistance have been developed. Hip simulator studies have demonstrated very low wear rates with these new materials leading to their widespread c...

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Veröffentlicht in:	Biomaterials 2003-07, Vol.24 (15), p.2561-2573
Hauptverfasser:	Sethi, Rajiv K, Neavyn, Mark J, Rubash, Harry E, Shanbhag, Arun S
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biocompatible Materials - chemistry Cell Culture Techniques - methods Cells, Cultured Chromium Alloys Cross-linked UHMWPE Cytokines Cytokines - genetics Cytokines - metabolism Foreign-Body Reaction Humans Inflammation Macrophages Macrophages - cytology Macrophages - immunology Materials Testing Mice Monocytes - cytology Monocytes - immunology Polyethylenes - chemistry RNA - metabolism Titanium - chemistry Total joint replacement
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