Identification of an activating transcription factor (ATF) binding site in the human transforming growth factor-beta 2 promoter

Transforming growth factor TGF-beta 2 is encoded by multiple mRNA transcripts of 5.8, 5.1, 4.0, 3.8, and 2.8 kilobase pairs (kb) that are expressed in various human and monkey cells. Northern blot analysis using genomic fragments of DNA was used to demonstrate that some of this size heterogeneity is...

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Veröffentlicht in:	The Journal of biological chemistry 1992-10, Vol.267 (28), p.19938-19943
Hauptverfasser:	O'Reilly, M A, Geiser, A G, Kim, S J, Bruggeman, L A, Luu, A X, Roberts, A B, Sporn, M B
Format:	Artikel
Sprache:	eng
Schlagworte:	Activating Transcription Factors Binding Sites Blood Proteins - metabolism Blotting, Northern Cells, Cultured Chloramphenicol O-Acetyltransferase - genetics Cyclic AMP Response Element-Binding Protein - metabolism DNA - metabolism DNA Probes Enhancer Elements, Genetic Humans Mutation Plasmids Promoter Regions, Genetic RNA, Messenger - genetics TATA Box Transcription Factors - metabolism Transforming Growth Factor beta - genetics Tumor Cells, Cultured
Online-Zugang:	Volltext
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