Diffuse lymphoid tissue associated with the human bulbourethral gland. An immunohistologic characterization
This study investigates the presence and distribution of immunocompetent cells in bulbourethral glands obtained from four multiorgan transplant donors. Monoclonal antibodies reacting with B (Leu 12 +) and T (Leu 4 +) cells, suppressor‐cytotoxic cells (Leu 2a +), helper‐inducer (Leu 3a +) and natural...
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| Veröffentlicht in: | Journal of andrology 1992-07, Vol.13 (4), p.337-341 |
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| creator | Migliari, R Riva, A Lantini, M. S Melis, M Usai, E |
| description | This study investigates the presence and distribution of immunocompetent cells in bulbourethral glands obtained from four multiorgan transplant donors. Monoclonal antibodies reacting with B (Leu 12 +) and T (Leu 4 +) cells, suppressor‐cytotoxic cells (Leu 2a +), helper‐inducer (Leu 3a +) and natural killer (Leu 7 +) phenotypes, monocyte‐macrophages, (LeuM3 +), and cells expressing interleukin‐2 receptor and HLA‐DR antigen were tested in all specimens using an indirect immunoperoxidase staining procedure. T lymphocytes were estimated to represent 10% of the mucosal cell population. Almost all intraepithelial lymphocytes were suppressor‐cytotoxic (CD8 +) cells. The results demonstrate the presence of a defined distribution of immunocompetent cells in these sex accessory glands. Their role in combatting infections or other chronic genitourinary diseases is still undefined. |
| doi_str_mv | 10.1002/j.1939-4640.1992.tb00333.x |
| format | Article |
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An immunohistologic characterization</title><source>MEDLINE</source><source>Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals</source><creator>Migliari, R ; Riva, A ; Lantini, M. S ; Melis, M ; Usai, E</creator><creatorcontrib>Migliari, R ; Riva, A ; Lantini, M. S ; Melis, M ; Usai, E</creatorcontrib><description>This study investigates the presence and distribution of immunocompetent cells in bulbourethral glands obtained from four multiorgan transplant donors. Monoclonal antibodies reacting with B (Leu 12 +) and T (Leu 4 +) cells, suppressor‐cytotoxic cells (Leu 2a +), helper‐inducer (Leu 3a +) and natural killer (Leu 7 +) phenotypes, monocyte‐macrophages, (LeuM3 +), and cells expressing interleukin‐2 receptor and HLA‐DR antigen were tested in all specimens using an indirect immunoperoxidase staining procedure. T lymphocytes were estimated to represent 10% of the mucosal cell population. Almost all intraepithelial lymphocytes were suppressor‐cytotoxic (CD8 +) cells. The results demonstrate the presence of a defined distribution of immunocompetent cells in these sex accessory glands. Their role in combatting infections or other chronic genitourinary diseases is still undefined.</description><identifier>ISSN: 0196-3635</identifier><identifier>EISSN: 1939-4640</identifier><identifier>DOI: 10.1002/j.1939-4640.1992.tb00333.x</identifier><identifier>PMID: 1399836</identifier><identifier>CODEN: JOAND3</identifier><language>eng</language><publisher>Oxford, UK: Am Soc Andrology</publisher><subject>Adult ; Antibodies, Monoclonal - analysis ; Antibodies, Monoclonal - immunology ; Antigens, Differentiation, B-Lymphocyte - immunology ; Antigens, Differentiation, T-Lymphocyte - immunology ; Biological and medical sciences ; Bulbourethral gland ; Bulbourethral Glands - chemistry ; Bulbourethral Glands - cytology ; Bulbourethral Glands - physiology ; Fundamental and applied biological sciences. Psychology ; HLA-DR Antigens - immunology ; Humans ; immune system ; Immunohistochemistry ; Lymphoid Tissue - chemistry ; Lymphoid Tissue - cytology ; Lymphoid Tissue - physiology ; Male ; Mammalian male genital system ; Morphology. Physiology ; Receptors, Interleukin-2 - immunology ; Vertebrates: reproduction</subject><ispartof>Journal of andrology, 1992-07, Vol.13 (4), p.337-341</ispartof><rights>1992 American Society of Andrology</rights><rights>1992 INIST-CNRS</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c4243-7b09a4789322a78998d1c1ac85961435eb0ba88063347a08a02ed90fc7ed31fc3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=5476311$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/1399836$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Migliari, R</creatorcontrib><creatorcontrib>Riva, A</creatorcontrib><creatorcontrib>Lantini, M. S</creatorcontrib><creatorcontrib>Melis, M</creatorcontrib><creatorcontrib>Usai, E</creatorcontrib><title>Diffuse lymphoid tissue associated with the human bulbourethral gland. An immunohistologic characterization</title><title>Journal of andrology</title><addtitle>J Androl</addtitle><description>This study investigates the presence and distribution of immunocompetent cells in bulbourethral glands obtained from four multiorgan transplant donors. Monoclonal antibodies reacting with B (Leu 12 +) and T (Leu 4 +) cells, suppressor‐cytotoxic cells (Leu 2a +), helper‐inducer (Leu 3a +) and natural killer (Leu 7 +) phenotypes, monocyte‐macrophages, (LeuM3 +), and cells expressing interleukin‐2 receptor and HLA‐DR antigen were tested in all specimens using an indirect immunoperoxidase staining procedure. T lymphocytes were estimated to represent 10% of the mucosal cell population. Almost all intraepithelial lymphocytes were suppressor‐cytotoxic (CD8 +) cells. The results demonstrate the presence of a defined distribution of immunocompetent cells in these sex accessory glands. Their role in combatting infections or other chronic genitourinary diseases is still undefined.</description><subject>Adult</subject><subject>Antibodies, Monoclonal - analysis</subject><subject>Antibodies, Monoclonal - immunology</subject><subject>Antigens, Differentiation, B-Lymphocyte - immunology</subject><subject>Antigens, Differentiation, T-Lymphocyte - immunology</subject><subject>Biological and medical sciences</subject><subject>Bulbourethral gland</subject><subject>Bulbourethral Glands - chemistry</subject><subject>Bulbourethral Glands - cytology</subject><subject>Bulbourethral Glands - physiology</subject><subject>Fundamental and applied biological sciences. Psychology</subject><subject>HLA-DR Antigens - immunology</subject><subject>Humans</subject><subject>immune system</subject><subject>Immunohistochemistry</subject><subject>Lymphoid Tissue - chemistry</subject><subject>Lymphoid Tissue - cytology</subject><subject>Lymphoid Tissue - physiology</subject><subject>Male</subject><subject>Mammalian male genital system</subject><subject>Morphology. Physiology</subject><subject>Receptors, Interleukin-2 - immunology</subject><subject>Vertebrates: reproduction</subject><issn>0196-3635</issn><issn>1939-4640</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1992</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqVkEuP0zAUhS0EGsrAT0CyELBLsXPTJGaDqnnw0Ag2sLZuHKdxceKO7ShTfj2uUg1rVtfyOefeo4-QN5ytOWP5h_2aCxBZURbpQ4h8HRvGAGD98ISsHqWnZMW4KDMoYfOcvAhhn7KMV3BBLjgIUUO5Ir-vTddNQVN7HA69My2NJoRJUwzBKYNRt3Q2saex17SfBhxpM9nGTV7H3qOlO4tju6bbkZphmEbXmxCddTujqOrRo4ramz8YjRtfkmcd2qBfnecl-XV78_PqS3b34_PXq-1dpoq8gKxqmMCiqgXkOaYh6pYrjqreiJIXsNENa7CuWQlQVMhqZLluBetUpVvgnYJL8n7Ze_DuftIhysEEpW1qqt0UZAU51GUpkvHjYlTeheB1Jw_eDOiPkjN5Ii338oRTnnDKE2l5Ji0fUvj1-crUDLr9F13QJv3tWceg0HYeR2XCo21TVCVwnmyfFttsrD7-RwH5bfv9Or3ShnfLht7s-tl4LcOA1qZaXM7zzEEWEqCCv63Pqc4</recordid><startdate>199207</startdate><enddate>199207</enddate><creator>Migliari, R</creator><creator>Riva, A</creator><creator>Lantini, M. S</creator><creator>Melis, M</creator><creator>Usai, E</creator><general>Am Soc Andrology</general><general>Blackwell Publishing Ltd</general><general>American Society of Andrology</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>199207</creationdate><title>Diffuse lymphoid tissue associated with the human bulbourethral gland. An immunohistologic characterization</title><author>Migliari, R ; Riva, A ; Lantini, M. S ; Melis, M ; Usai, E</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4243-7b09a4789322a78998d1c1ac85961435eb0ba88063347a08a02ed90fc7ed31fc3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1992</creationdate><topic>Adult</topic><topic>Antibodies, Monoclonal - analysis</topic><topic>Antibodies, Monoclonal - immunology</topic><topic>Antigens, Differentiation, B-Lymphocyte - immunology</topic><topic>Antigens, Differentiation, T-Lymphocyte - immunology</topic><topic>Biological and medical sciences</topic><topic>Bulbourethral gland</topic><topic>Bulbourethral Glands - chemistry</topic><topic>Bulbourethral Glands - cytology</topic><topic>Bulbourethral Glands - physiology</topic><topic>Fundamental and applied biological sciences. Psychology</topic><topic>HLA-DR Antigens - immunology</topic><topic>Humans</topic><topic>immune system</topic><topic>Immunohistochemistry</topic><topic>Lymphoid Tissue - chemistry</topic><topic>Lymphoid Tissue - cytology</topic><topic>Lymphoid Tissue - physiology</topic><topic>Male</topic><topic>Mammalian male genital system</topic><topic>Morphology. Physiology</topic><topic>Receptors, Interleukin-2 - immunology</topic><topic>Vertebrates: reproduction</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Migliari, R</creatorcontrib><creatorcontrib>Riva, A</creatorcontrib><creatorcontrib>Lantini, M. S</creatorcontrib><creatorcontrib>Melis, M</creatorcontrib><creatorcontrib>Usai, E</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of andrology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Migliari, R</au><au>Riva, A</au><au>Lantini, M. S</au><au>Melis, M</au><au>Usai, E</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Diffuse lymphoid tissue associated with the human bulbourethral gland. An immunohistologic characterization</atitle><jtitle>Journal of andrology</jtitle><addtitle>J Androl</addtitle><date>1992-07</date><risdate>1992</risdate><volume>13</volume><issue>4</issue><spage>337</spage><epage>341</epage><pages>337-341</pages><issn>0196-3635</issn><eissn>1939-4640</eissn><coden>JOAND3</coden><abstract>This study investigates the presence and distribution of immunocompetent cells in bulbourethral glands obtained from four multiorgan transplant donors. Monoclonal antibodies reacting with B (Leu 12 +) and T (Leu 4 +) cells, suppressor‐cytotoxic cells (Leu 2a +), helper‐inducer (Leu 3a +) and natural killer (Leu 7 +) phenotypes, monocyte‐macrophages, (LeuM3 +), and cells expressing interleukin‐2 receptor and HLA‐DR antigen were tested in all specimens using an indirect immunoperoxidase staining procedure. T lymphocytes were estimated to represent 10% of the mucosal cell population. Almost all intraepithelial lymphocytes were suppressor‐cytotoxic (CD8 +) cells. The results demonstrate the presence of a defined distribution of immunocompetent cells in these sex accessory glands. Their role in combatting infections or other chronic genitourinary diseases is still undefined.</abstract><cop>Oxford, UK</cop><pub>Am Soc Andrology</pub><pmid>1399836</pmid><doi>10.1002/j.1939-4640.1992.tb00333.x</doi><tpages>5</tpages><oa>free_for_read</oa></addata></record> |
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| subjects | Adult Antibodies, Monoclonal - analysis Antibodies, Monoclonal - immunology Antigens, Differentiation, B-Lymphocyte - immunology Antigens, Differentiation, T-Lymphocyte - immunology Biological and medical sciences Bulbourethral gland Bulbourethral Glands - chemistry Bulbourethral Glands - cytology Bulbourethral Glands - physiology Fundamental and applied biological sciences. Psychology HLA-DR Antigens - immunology Humans immune system Immunohistochemistry Lymphoid Tissue - chemistry Lymphoid Tissue - cytology Lymphoid Tissue - physiology Male Mammalian male genital system Morphology. Physiology Receptors, Interleukin-2 - immunology Vertebrates: reproduction |
| title | Diffuse lymphoid tissue associated with the human bulbourethral gland. An immunohistologic characterization |
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