Inhalational Anesthetic Technique in Microlaryngeal Surgery: A Comparison between Sevoflurane-Remifentanil and Sevoflurane-Alfentanil Anesthesia
We studied the effects of sevoflurane, remifentanil hydrochloride, and alfentanil anesthesia in terms of the hemodynamic responses and emergence characteristics of patients scheduled for elective microlaryngeal surgery. Sixty patients (ASA I to III) were randomly allocated into 2 groups: group S-R (...
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| Veröffentlicht in: | Annals of otology, rhinology & laryngology rhinology & laryngology, 2003-04, Vol.112 (4), p.373-378 |
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| container_title | Annals of otology, rhinology & laryngology |
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| creator | Pandazi, Ageliki K. Louizos, Antonios A. Stivaktakis, John M. Davilis, Dimitrios J. Georgiou, Loucas G. |
| description | We studied the effects of sevoflurane, remifentanil hydrochloride, and alfentanil anesthesia in terms of the hemodynamic responses and emergence characteristics of patients scheduled for elective microlaryngeal surgery. Sixty patients (ASA I to III) were randomly allocated into 2 groups: group S-R (sevoflurane-remifentanil) and group S-A (sevoflurane-alfentanil; 1:20 and 1:4 ratios of remifentanil to alfentanil for induction and maintenance of anesthesia, respectively; doses not strictly equipotent). The mean arterial pressure and heart rate were measured before and after induction of anesthesia, 1 and 3 minutes after endotracheal intubation, at the insertion of the operating laryngoscope, and every 3 minutes during surgery. The emergence times and side effects during the first 30 minutes after surgery were also recorded. The mean arterial pressure values at the insertion of the operating laryngoscope and throughout the procedure were significantly greater (p < .05) in group S-A than in group S-R. The emergence times and postoperative side effects did not differ, except for the greater pain score (p < .05) in group S-R. In conclusion, sevoflurane with remifentanil seems to maintain cardiovascular stability during microlaryngeal surgery more effectively than sevoflurane with alfentanil. Both anesthetic regimens seem to provide rapid and uneventful emergence. |
| doi_str_mv | 10.1177/000348940311200414 |
| format | Article |
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Sixty patients (ASA I to III) were randomly allocated into 2 groups: group S-R (sevoflurane-remifentanil) and group S-A (sevoflurane-alfentanil; 1:20 and 1:4 ratios of remifentanil to alfentanil for induction and maintenance of anesthesia, respectively; doses not strictly equipotent). The mean arterial pressure and heart rate were measured before and after induction of anesthesia, 1 and 3 minutes after endotracheal intubation, at the insertion of the operating laryngoscope, and every 3 minutes during surgery. The emergence times and side effects during the first 30 minutes after surgery were also recorded. The mean arterial pressure values at the insertion of the operating laryngoscope and throughout the procedure were significantly greater (p < .05) in group S-A than in group S-R. The emergence times and postoperative side effects did not differ, except for the greater pain score (p < .05) in group S-R. In conclusion, sevoflurane with remifentanil seems to maintain cardiovascular stability during microlaryngeal surgery more effectively than sevoflurane with alfentanil. Both anesthetic regimens seem to provide rapid and uneventful emergence.</description><identifier>ISSN: 0003-4894</identifier><identifier>EISSN: 1943-572X</identifier><identifier>DOI: 10.1177/000348940311200414</identifier><identifier>PMID: 12731635</identifier><identifier>CODEN: AORHA2</identifier><language>eng</language><publisher>Los Angeles, CA: SAGE Publications</publisher><subject>Administration, Inhalation ; Adult ; Aged ; Alfentanil - administration & dosage ; Analgesics, Opioid - administration & dosage ; Anesthesia, General - methods ; Anesthetics, Inhalation - administration & dosage ; Biological and medical sciences ; Female ; Head and neck surgery. Maxillofacial surgery. Dental surgery. Orthodontics ; Heart Rate - physiology ; Hemodynamics - physiology ; Humans ; Laryngoscopy - methods ; Larynx - blood supply ; Male ; Medical sciences ; Methyl Ethers - administration & dosage ; Microsurgery - methods ; Middle Aged ; Non tumoral diseases ; Otorhinolaryngology. Stomatology ; Piperidines - administration & dosage ; Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases ; Surgery of the upper aerodigestive tract ; Upper respiratory tract, upper alimentary tract, paranasal sinuses, salivary glands: diseases, semeiology</subject><ispartof>Annals of otology, rhinology & laryngology, 2003-04, Vol.112 (4), p.373-378</ispartof><rights>2003 SAGE Publications</rights><rights>2003 INIST-CNRS</rights><rights>Copyright Annals Publishing Company Apr 2003</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c396t-15e6980984750bad608eb77cb133b3a35f38cf125281ef35000ad30f584de74b3</citedby><cites>FETCH-LOGICAL-c396t-15e6980984750bad608eb77cb133b3a35f38cf125281ef35000ad30f584de74b3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://journals.sagepub.com/doi/pdf/10.1177/000348940311200414$$EPDF$$P50$$Gsage$$H</linktopdf><linktohtml>$$Uhttps://journals.sagepub.com/doi/10.1177/000348940311200414$$EHTML$$P50$$Gsage$$H</linktohtml><link.rule.ids>314,776,780,21798,27901,27902,43597,43598</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=14734316$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/12731635$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Pandazi, Ageliki K.</creatorcontrib><creatorcontrib>Louizos, Antonios A.</creatorcontrib><creatorcontrib>Stivaktakis, John M.</creatorcontrib><creatorcontrib>Davilis, Dimitrios J.</creatorcontrib><creatorcontrib>Georgiou, Loucas G.</creatorcontrib><title>Inhalational Anesthetic Technique in Microlaryngeal Surgery: A Comparison between Sevoflurane-Remifentanil and Sevoflurane-Alfentanil Anesthesia</title><title>Annals of otology, rhinology & laryngology</title><addtitle>Ann Otol Rhinol Laryngol</addtitle><description>We studied the effects of sevoflurane, remifentanil hydrochloride, and alfentanil anesthesia in terms of the hemodynamic responses and emergence characteristics of patients scheduled for elective microlaryngeal surgery. Sixty patients (ASA I to III) were randomly allocated into 2 groups: group S-R (sevoflurane-remifentanil) and group S-A (sevoflurane-alfentanil; 1:20 and 1:4 ratios of remifentanil to alfentanil for induction and maintenance of anesthesia, respectively; doses not strictly equipotent). The mean arterial pressure and heart rate were measured before and after induction of anesthesia, 1 and 3 minutes after endotracheal intubation, at the insertion of the operating laryngoscope, and every 3 minutes during surgery. The emergence times and side effects during the first 30 minutes after surgery were also recorded. The mean arterial pressure values at the insertion of the operating laryngoscope and throughout the procedure were significantly greater (p < .05) in group S-A than in group S-R. The emergence times and postoperative side effects did not differ, except for the greater pain score (p < .05) in group S-R. In conclusion, sevoflurane with remifentanil seems to maintain cardiovascular stability during microlaryngeal surgery more effectively than sevoflurane with alfentanil. Both anesthetic regimens seem to provide rapid and uneventful emergence.</description><subject>Administration, Inhalation</subject><subject>Adult</subject><subject>Aged</subject><subject>Alfentanil - administration & dosage</subject><subject>Analgesics, Opioid - administration & dosage</subject><subject>Anesthesia, General - methods</subject><subject>Anesthetics, Inhalation - administration & dosage</subject><subject>Biological and medical sciences</subject><subject>Female</subject><subject>Head and neck surgery. Maxillofacial surgery. Dental surgery. Orthodontics</subject><subject>Heart Rate - physiology</subject><subject>Hemodynamics - physiology</subject><subject>Humans</subject><subject>Laryngoscopy - methods</subject><subject>Larynx - blood supply</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Methyl Ethers - administration & dosage</subject><subject>Microsurgery - methods</subject><subject>Middle Aged</subject><subject>Non tumoral diseases</subject><subject>Otorhinolaryngology. Stomatology</subject><subject>Piperidines - administration & dosage</subject><subject>Surgery (general aspects). Transplantations, organ and tissue grafts. 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Sixty patients (ASA I to III) were randomly allocated into 2 groups: group S-R (sevoflurane-remifentanil) and group S-A (sevoflurane-alfentanil; 1:20 and 1:4 ratios of remifentanil to alfentanil for induction and maintenance of anesthesia, respectively; doses not strictly equipotent). The mean arterial pressure and heart rate were measured before and after induction of anesthesia, 1 and 3 minutes after endotracheal intubation, at the insertion of the operating laryngoscope, and every 3 minutes during surgery. The emergence times and side effects during the first 30 minutes after surgery were also recorded. The mean arterial pressure values at the insertion of the operating laryngoscope and throughout the procedure were significantly greater (p < .05) in group S-A than in group S-R. The emergence times and postoperative side effects did not differ, except for the greater pain score (p < .05) in group S-R. In conclusion, sevoflurane with remifentanil seems to maintain cardiovascular stability during microlaryngeal surgery more effectively than sevoflurane with alfentanil. Both anesthetic regimens seem to provide rapid and uneventful emergence.</abstract><cop>Los Angeles, CA</cop><pub>SAGE Publications</pub><pmid>12731635</pmid><doi>10.1177/000348940311200414</doi><tpages>6</tpages></addata></record> |
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| subjects | Administration, Inhalation Adult Aged Alfentanil - administration & dosage Analgesics, Opioid - administration & dosage Anesthesia, General - methods Anesthetics, Inhalation - administration & dosage Biological and medical sciences Female Head and neck surgery. Maxillofacial surgery. Dental surgery. Orthodontics Heart Rate - physiology Hemodynamics - physiology Humans Laryngoscopy - methods Larynx - blood supply Male Medical sciences Methyl Ethers - administration & dosage Microsurgery - methods Middle Aged Non tumoral diseases Otorhinolaryngology. Stomatology Piperidines - administration & dosage Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases Surgery of the upper aerodigestive tract Upper respiratory tract, upper alimentary tract, paranasal sinuses, salivary glands: diseases, semeiology |
| title | Inhalational Anesthetic Technique in Microlaryngeal Surgery: A Comparison between Sevoflurane-Remifentanil and Sevoflurane-Alfentanil Anesthesia |
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