The effect of maternal intravenous glucose administration on fetal activity

OBJECTIVE: The study was designed to objectively evaluate the effect of maternal intravenous glucoseinfusion on fetal activity. STUDY DESIGN: Twenty-one volunteers at 30.7 ± 3.0 weeks' gestation were objectively evaluated forfetal activity with a Doppler monitor before and during an intravenous...

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Veröffentlicht in:American journal of obstetrics and gynecology 1992-10, Vol.167 (4), p.1071-1074
Hauptverfasser: Eller, Daniel P., Stramm, Sue L., Newman, Roger B.
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container_end_page 1074
container_issue 4
container_start_page 1071
container_title American journal of obstetrics and gynecology
container_volume 167
creator Eller, Daniel P.
Stramm, Sue L.
Newman, Roger B.
description OBJECTIVE: The study was designed to objectively evaluate the effect of maternal intravenous glucoseinfusion on fetal activity. STUDY DESIGN: Twenty-one volunteers at 30.7 ± 3.0 weeks' gestation were objectively evaluated forfetal activity with a Doppler monitor before and during an intravenous glucose test. Baseline fetal activity monitoring began 10 minutes before a fasting blood glucose level was obtained. A standard 1-hour intravenous glucose tolerance test was then performed, and fetal activity monitoring was continued for the duration of the test. Twenty-one women at 29.8 ± 3.0 weeks' gestation volunteered to serve as controls and were continuously monitored for fetal activity. The control patients did not receive intravenous glucose. RESULTS: Linear regression analysis revealed an increase in fetal activity in both groups; however, theincrease in the glucose infusion group was significantly greater than in the control group. CONCLUSIONS: Maternal glucose infusion causes short-term stimulation of fetal activity; however, someother factor in the monitoring process also stimulates fetal activity. ( Am J Obstet Gynecol 1992;167: 1071–4.)
doi_str_mv 10.1016/S0002-9378(12)80040-8
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STUDY DESIGN: Twenty-one volunteers at 30.7 ± 3.0 weeks' gestation were objectively evaluated forfetal activity with a Doppler monitor before and during an intravenous glucose test. Baseline fetal activity monitoring began 10 minutes before a fasting blood glucose level was obtained. A standard 1-hour intravenous glucose tolerance test was then performed, and fetal activity monitoring was continued for the duration of the test. Twenty-one women at 29.8 ± 3.0 weeks' gestation volunteered to serve as controls and were continuously monitored for fetal activity. The control patients did not receive intravenous glucose. RESULTS: Linear regression analysis revealed an increase in fetal activity in both groups; however, theincrease in the glucose infusion group was significantly greater than in the control group. CONCLUSIONS: Maternal glucose infusion causes short-term stimulation of fetal activity; however, someother factor in the monitoring process also stimulates fetal activity. ( Am J Obstet Gynecol 1992;167: 1071–4.)</description><subject>Biological and medical sciences</subject><subject>Blood Glucose - analysis</subject><subject>Female</subject><subject>Fetal Movement - drug effects</subject><subject>Glucose - pharmacology</subject><subject>Glucose Tolerance Test</subject><subject>Gynecology. Andrology. Obstetrics</subject><subject>Humans</subject><subject>Infusions, Intravenous</subject><subject>Key words: Fetal activity, actograph, glucose infusion</subject><subject>Management. Prenatal diagnosis</subject><subject>Maternal-Fetal Exchange</subject><subject>Medical sciences</subject><subject>Pregnancy - blood</subject><subject>Pregnancy. Fetus. 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Andrology. Obstetrics</topic><topic>Humans</topic><topic>Infusions, Intravenous</topic><topic>Key words: Fetal activity, actograph, glucose infusion</topic><topic>Management. Prenatal diagnosis</topic><topic>Maternal-Fetal Exchange</topic><topic>Medical sciences</topic><topic>Pregnancy - blood</topic><topic>Pregnancy. Fetus. Placenta</topic><topic>Regression Analysis</topic><topic>Time Factors</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Eller, Daniel P.</creatorcontrib><creatorcontrib>Stramm, Sue L.</creatorcontrib><creatorcontrib>Newman, Roger B.</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>American journal of obstetrics and gynecology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Eller, Daniel P.</au><au>Stramm, Sue L.</au><au>Newman, Roger B.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>The effect of maternal intravenous glucose administration on fetal activity</atitle><jtitle>American journal of obstetrics and gynecology</jtitle><addtitle>Am J Obstet Gynecol</addtitle><date>1992-10-01</date><risdate>1992</risdate><volume>167</volume><issue>4</issue><spage>1071</spage><epage>1074</epage><pages>1071-1074</pages><issn>0002-9378</issn><eissn>1097-6868</eissn><coden>AJOGAH</coden><abstract>OBJECTIVE: The study was designed to objectively evaluate the effect of maternal intravenous glucoseinfusion on fetal activity. STUDY DESIGN: Twenty-one volunteers at 30.7 ± 3.0 weeks' gestation were objectively evaluated forfetal activity with a Doppler monitor before and during an intravenous glucose test. Baseline fetal activity monitoring began 10 minutes before a fasting blood glucose level was obtained. A standard 1-hour intravenous glucose tolerance test was then performed, and fetal activity monitoring was continued for the duration of the test. Twenty-one women at 29.8 ± 3.0 weeks' gestation volunteered to serve as controls and were continuously monitored for fetal activity. The control patients did not receive intravenous glucose. RESULTS: Linear regression analysis revealed an increase in fetal activity in both groups; however, theincrease in the glucose infusion group was significantly greater than in the control group. CONCLUSIONS: Maternal glucose infusion causes short-term stimulation of fetal activity; however, someother factor in the monitoring process also stimulates fetal activity. 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source MEDLINE; Access via ScienceDirect (Elsevier)
subjects Biological and medical sciences
Blood Glucose - analysis
Female
Fetal Movement - drug effects
Glucose - pharmacology
Glucose Tolerance Test
Gynecology. Andrology. Obstetrics
Humans
Infusions, Intravenous
Key words: Fetal activity, actograph, glucose infusion
Management. Prenatal diagnosis
Maternal-Fetal Exchange
Medical sciences
Pregnancy - blood
Pregnancy. Fetus. Placenta
Regression Analysis
Time Factors
title The effect of maternal intravenous glucose administration on fetal activity
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