Neurotrophic action of gliostatin on cortical neurons. Identity of gliostatin and platelet-derived endothelial cell growth factor

Gliostatin is a polypeptide growth inhibitor of apparent M(r) = 100,000 with a homodimeric structure comprising two 50-kDa subunits, acting on astrocyte as well as astrocytoma cells (Asai, K., Hirano, T., Kaneko, S., Moriyama, A., Nakanishi, K., Isobe, I., Eksioglu, Y.Z., and Kato, T. (1992) J. Neur...

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Veröffentlicht in:	The Journal of biological chemistry 1992-10, Vol.267 (28), p.20311-20316
Hauptverfasser:	ASAI, K, NAKANISHI, K, ISOBE, I, EKSIOGLU, Y. Z, HIRANO, A, HAMA, K, MIYAMOTO, T, KATO, T
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Analytical, structural and metabolic biochemistry Animals Antibodies, Monoclonal - immunology Biological and medical sciences Cattle Cells, Cultured Cerebral Cortex - cytology Electrophoresis, Polyacrylamide Gel Endothelium, Vascular - cytology Fundamental and applied biological sciences. Psychology Growth Inhibitors - immunology Growth Inhibitors - metabolism Growth Inhibitors - physiology Molecular Sequence Data Nerve Tissue Proteins - immunology Nerve Tissue Proteins - metabolism Nerve Tissue Proteins - physiology Neurons - cytology Peptide Mapping Protein hormones. Growth factors. Cytokines Proteins Rats Thymidine Phosphorylase - immunology Thymidine Phosphorylase - metabolism Thymidine Phosphorylase - physiology Tumor Cells, Cultured
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