Ectopic LT alpha beta directs lymphoid organ neogenesis with concomitant expression of peripheral node addressin and a HEV-restricted sulfotransferase

Lymph node (LN) function depends on T and B cell compartmentalization, antigen presenting cells, and high endothelial venules (HEVs) expressing mucosal addressin cell adhesion molecule (MAdCAM-1) and peripheral node addressin (PNAd), ligands for naive cell entrance into LNs. Luminal PNAd expression...

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Veröffentlicht in:	The Journal of experimental medicine 2003-05, Vol.197 (9), p.1153-1163
Hauptverfasser:	Drayton, Danielle L, Ying, Xiaoyan, Lee, Jason, Lesslauer, Werner, Ruddle, Nancy H
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Enzyme Induction Immunohistochemistry Lymphoid Tissue - embryology Lymphotoxin-alpha - physiology Lymphotoxin-beta Membrane Proteins - physiology Mice Mice, Transgenic Sulfotransferases - biosynthesis Sulfotransferases - metabolism
Online-Zugang:	Volltext
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