Inhibition of nicotine-induced relaxation of the bovine retractor penis muscle by β-adrenoceptor antagonists

The relative potency in inhibiting nicotine-induced relaxation of the bovine retractor penis muscle (BRP) was estimated for the racemates of seven β-adrenoceptor antagonists, both of the optical isomers of propranolol, and lidocaine. The order of potency of the drugs studied was (+)-propranolol>(...

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Veröffentlicht in:	Pharmacological research 1992-05, Vol.25 (4), p.353-361
Hauptverfasser:	Klinge, Erik, Alaranta, Sakari, Nissinen, Ritva, Sjo¨strand, Nils O.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adrenergic beta-Antagonists - pharmacology Animals Cattle Lidocaine - pharmacology Male Muscle Relaxation - drug effects Nicotine - antagonists & inhibitors penile erection penis Penis - drug effects Penis - physiology Propranolol - pharmacology Regression Analysis β-adrenergic blocking agents
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