Manual transport in Parkinson's disease
We analyze hand dexterity in Parkinson's disease patients (PD) and control subjects using a natural manual transport task (moving an object from one place to another). Eight PD patients and 10 control subjects carried out the task repeatedly at maximum speed both in off and on medicated status....
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| Veröffentlicht in: | Movement disorders 2003-05, Vol.18 (5), p.565-572 |
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| container_title | Movement disorders |
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| creator | Hejduková, Blanka Hosseini, Nasser Johnels, Bo Ingvarsson, Pall E. Steg, Göran Olsson, Torsten |
| description | We analyze hand dexterity in Parkinson's disease patients (PD) and control subjects using a natural manual transport task (moving an object from one place to another). Eight PD patients and 10 control subjects carried out the task repeatedly at maximum speed both in off and on medicated status. The movement parameters and the grip and load forces were recorded. Using the force and velocity signals, 10 subsequent phases of the transport movement were defined and their durations were measured. The difference between the control group and the test group in off and on was established statistically using non‐parametric methods. There was slowed reaching and a striking disturbance of establishing the precision grip in PD. The transport capabilities were impaired differentially. Although acceleration and reaching sufficient height of the lift were disturbed in PD subjects, transport of the object toward the target position was almost normal. A partial disturbance was observed when cancelling the grip. Dopaminergic medication improved only specific hand skills, especially establishment of the precision grip and one of the four transport phases. A long movement path was more sensitive for movement disturbance in Parkinson's disease than a short one.© 2003 Movement Disorder Society |
| doi_str_mv | 10.1002/mds.10402 |
| format | Article |
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Eight PD patients and 10 control subjects carried out the task repeatedly at maximum speed both in off and on medicated status. The movement parameters and the grip and load forces were recorded. Using the force and velocity signals, 10 subsequent phases of the transport movement were defined and their durations were measured. The difference between the control group and the test group in off and on was established statistically using non‐parametric methods. There was slowed reaching and a striking disturbance of establishing the precision grip in PD. The transport capabilities were impaired differentially. Although acceleration and reaching sufficient height of the lift were disturbed in PD subjects, transport of the object toward the target position was almost normal. A partial disturbance was observed when cancelling the grip. Dopaminergic medication improved only specific hand skills, especially establishment of the precision grip and one of the four transport phases. 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Prion diseases ; Female ; Functional Laterality - physiology ; Hand - physiopathology ; Hand Strength - physiology ; Humans ; Male ; manual transport ; Medical sciences ; Middle Aged ; movement phases ; Neurology ; Parkinson Disease - drug therapy ; Parkinson Disease - physiopathology ; Parkinson's disease ; Psychomotor Performance - drug effects ; Psychomotor Performance - physiology ; Time Factors</subject><ispartof>Movement disorders, 2003-05, Vol.18 (5), p.565-572</ispartof><rights>Copyright © 2003 Movement Disorders Society</rights><rights>2003 INIST-CNRS</rights><rights>Copyright 2003 Movement Disorder Society</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4202-5d842b27353243777832281c783a09b3cad3e6fd4a994c7e67f52641d7014db13</citedby><cites>FETCH-LOGICAL-c4202-5d842b27353243777832281c783a09b3cad3e6fd4a994c7e67f52641d7014db13</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1002%2Fmds.10402$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1002%2Fmds.10402$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,776,780,1411,27901,27902,45550,45551</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=14805564$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/12722171$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Hejduková, Blanka</creatorcontrib><creatorcontrib>Hosseini, Nasser</creatorcontrib><creatorcontrib>Johnels, Bo</creatorcontrib><creatorcontrib>Ingvarsson, Pall E.</creatorcontrib><creatorcontrib>Steg, Göran</creatorcontrib><creatorcontrib>Olsson, Torsten</creatorcontrib><title>Manual transport in Parkinson's disease</title><title>Movement disorders</title><addtitle>Mov. Disord</addtitle><description>We analyze hand dexterity in Parkinson's disease patients (PD) and control subjects using a natural manual transport task (moving an object from one place to another). Eight PD patients and 10 control subjects carried out the task repeatedly at maximum speed both in off and on medicated status. The movement parameters and the grip and load forces were recorded. Using the force and velocity signals, 10 subsequent phases of the transport movement were defined and their durations were measured. The difference between the control group and the test group in off and on was established statistically using non‐parametric methods. There was slowed reaching and a striking disturbance of establishing the precision grip in PD. The transport capabilities were impaired differentially. Although acceleration and reaching sufficient height of the lift were disturbed in PD subjects, transport of the object toward the target position was almost normal. A partial disturbance was observed when cancelling the grip. Dopaminergic medication improved only specific hand skills, especially establishment of the precision grip and one of the four transport phases. A long movement path was more sensitive for movement disturbance in Parkinson's disease than a short one.© 2003 Movement Disorder Society</description><subject>Aged</subject><subject>Antiparkinson Agents - pharmacology</subject><subject>Antiparkinson Agents - therapeutic use</subject><subject>Automatic Data Processing</subject><subject>Biological and medical sciences</subject><subject>Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases</subject><subject>Female</subject><subject>Functional Laterality - physiology</subject><subject>Hand - physiopathology</subject><subject>Hand Strength - physiology</subject><subject>Humans</subject><subject>Male</subject><subject>manual transport</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>movement phases</subject><subject>Neurology</subject><subject>Parkinson Disease - drug therapy</subject><subject>Parkinson Disease - physiopathology</subject><subject>Parkinson's disease</subject><subject>Psychomotor Performance - drug effects</subject><subject>Psychomotor Performance - physiology</subject><subject>Time Factors</subject><issn>0885-3185</issn><issn>1531-8257</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2003</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkU1PwkAQhjdGI4ge_AOGixIPlZ3Z3W57NKgoAT-ixuNmabdJtbTYgSj_3kVQTsbTzOGZ902eYewQ-Blwjt1JSn6RHLdYE5SAIEKlt1mTR5EKBESqwfaIXjkHUBDusgagRgQNTdYZ2XJui_astiVNq3rWzsv2va3f8pKqskPtNCdnye2zncwW5A7Ws8Wery6fetfB8K5_0zsfBolEjoFKI4lj1EIJlEJrHQnECBI_LY_HIrGpcGGWShvHMtEu1JnCUEKqOch0DKLFTla507p6nzuamUlOiSsKW7pqTkYv87iP_w9EAIkopQdPV2BSV0S1y8y0zie2XhjgZqnPeH3mW59nj9ah8_HEpRty7csDx2vAUmKLzFtLctpwMuJKhcvS7or7yAu3-LvRjC4ef6qD1UVOM_f5e-E_YUIttDIvt33TjwcwjB_ADMQXgeaRsw</recordid><startdate>200305</startdate><enddate>200305</enddate><creator>Hejduková, Blanka</creator><creator>Hosseini, Nasser</creator><creator>Johnels, Bo</creator><creator>Ingvarsson, Pall E.</creator><creator>Steg, Göran</creator><creator>Olsson, Torsten</creator><general>Wiley Subscription Services, Inc., A Wiley Company</general><general>Wiley</general><scope>BSCLL</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7TK</scope><scope>7X8</scope><scope>8BM</scope></search><sort><creationdate>200305</creationdate><title>Manual transport in Parkinson's disease</title><author>Hejduková, Blanka ; Hosseini, Nasser ; Johnels, Bo ; Ingvarsson, Pall E. ; Steg, Göran ; Olsson, Torsten</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4202-5d842b27353243777832281c783a09b3cad3e6fd4a994c7e67f52641d7014db13</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2003</creationdate><topic>Aged</topic><topic>Antiparkinson Agents - pharmacology</topic><topic>Antiparkinson Agents - therapeutic use</topic><topic>Automatic Data Processing</topic><topic>Biological and medical sciences</topic><topic>Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases</topic><topic>Female</topic><topic>Functional Laterality - physiology</topic><topic>Hand - physiopathology</topic><topic>Hand Strength - physiology</topic><topic>Humans</topic><topic>Male</topic><topic>manual transport</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>movement phases</topic><topic>Neurology</topic><topic>Parkinson Disease - drug therapy</topic><topic>Parkinson Disease - physiopathology</topic><topic>Parkinson's disease</topic><topic>Psychomotor Performance - drug effects</topic><topic>Psychomotor Performance - physiology</topic><topic>Time Factors</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Hejduková, Blanka</creatorcontrib><creatorcontrib>Hosseini, Nasser</creatorcontrib><creatorcontrib>Johnels, Bo</creatorcontrib><creatorcontrib>Ingvarsson, Pall E.</creatorcontrib><creatorcontrib>Steg, Göran</creatorcontrib><creatorcontrib>Olsson, Torsten</creatorcontrib><collection>Istex</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Neurosciences Abstracts</collection><collection>MEDLINE - Academic</collection><collection>ComDisDome</collection><jtitle>Movement disorders</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Hejduková, Blanka</au><au>Hosseini, Nasser</au><au>Johnels, Bo</au><au>Ingvarsson, Pall E.</au><au>Steg, Göran</au><au>Olsson, Torsten</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Manual transport in Parkinson's disease</atitle><jtitle>Movement disorders</jtitle><addtitle>Mov. 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Although acceleration and reaching sufficient height of the lift were disturbed in PD subjects, transport of the object toward the target position was almost normal. A partial disturbance was observed when cancelling the grip. Dopaminergic medication improved only specific hand skills, especially establishment of the precision grip and one of the four transport phases. A long movement path was more sensitive for movement disturbance in Parkinson's disease than a short one.© 2003 Movement Disorder Society</abstract><cop>New York</cop><pub>Wiley Subscription Services, Inc., A Wiley Company</pub><pmid>12722171</pmid><doi>10.1002/mds.10402</doi><tpages>8</tpages></addata></record> |
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| subjects | Aged Antiparkinson Agents - pharmacology Antiparkinson Agents - therapeutic use Automatic Data Processing Biological and medical sciences Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases Female Functional Laterality - physiology Hand - physiopathology Hand Strength - physiology Humans Male manual transport Medical sciences Middle Aged movement phases Neurology Parkinson Disease - drug therapy Parkinson Disease - physiopathology Parkinson's disease Psychomotor Performance - drug effects Psychomotor Performance - physiology Time Factors |
| title | Manual transport in Parkinson's disease |
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