Single-Cell Transcriptional Analysis of Neuronal Progenitors

The extraordinary cellular heterogeneity of the mammalian nervous system has largely hindered the molecular analysis of neuronal identity and diversity. In order to uncover mechanisms involved in neuronal differentiation and diversification, we have monitored the expression profiles of individual ne...

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Veröffentlicht in:	Neuron (Cambridge, Mass.) Mass.), 2003-04, Vol.38 (2), p.161-175
Hauptverfasser:	Tietjen, Ian, Rihel, Jason M., Cao, Yanxiang, Koentges, Georgy, Zakhary, Lisa, Dulac, Catherine
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Basic Helix-Loop-Helix Transcription Factors Cell Differentiation Cell division Cell Separation - instrumentation Cell Separation - methods Cells, Cultured DNA, Complementary - analysis DNA, Complementary - genetics DNA-Binding Proteins - biosynthesis Gene expression Gene Expression Profiling - methods Gene Expression Regulation, Developmental Humans Hybridization Lasers Mice Neurogenesis Neuroglia - chemistry Neuroglia - cytology Neuroglia - metabolism Neurons Neurons - chemistry Neurons - cytology Neurons - metabolism Neurons, Afferent - chemistry Neurons, Afferent - cytology Neurons, Afferent - metabolism Nucleic Acid Hybridization Olfactory Mucosa - cytology Olfactory Mucosa - embryology Olfactory Mucosa - innervation Oligonucleotide Array Sequence Analysis Reproducibility of Results RNA, Messenger - genetics RNA, Messenger - metabolism Sensitivity and Specificity Signal Transduction - physiology Stem Cells - chemistry Stem Cells - cytology Stem Cells - metabolism Transcription Factors - biosynthesis Transcription, Genetic - physiology
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