Role of sequential leucocyte counts and C-reactive protein measurements in acute appendicitis
The accurate clinical diagnosis of acute appendicitis is dificult, and many techniques have been suggested to improve diagnostic accuracy such as laparoscopy, ultrasonography and barium enema examination. In this study serial total leucocyte counts and serial C‐reactive protein (CRP) concentrations...
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| Veröffentlicht in: | British journal of surgery 1992-08, Vol.79 (8), p.822-824 |
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| container_title | British journal of surgery |
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| creator | Thompson, M. M. Underwood, M. J. Dookeran, K. A. Lloyd, D. M. Bell, P. R. F. |
| description | The accurate clinical diagnosis of acute appendicitis is dificult, and many techniques have been suggested to improve diagnostic accuracy such as laparoscopy, ultrasonography and barium enema examination. In this study serial total leucocyte counts and serial C‐reactive protein (CRP) concentrations in acute appendicitis were measured. The sensitivity and specificity of serial leucocyte counts in acute appendicitis were 92 and 100 per cent, and for CRP concentrations 69 and 75 per cent, respectively. The sensitivity and specificity of serial total leucocyte counts fulfilled the criteria for a diagnostic test. It is suggested that in patients with equivocal clinical findings, clinical observation combined with serial leucocyte counts may improve decision making. |
| doi_str_mv | 10.1002/bjs.1800790839 |
| format | Article |
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M. ; Underwood, M. J. ; Dookeran, K. A. ; Lloyd, D. M. ; Bell, P. R. F.</creator><creatorcontrib>Thompson, M. M. ; Underwood, M. J. ; Dookeran, K. A. ; Lloyd, D. M. ; Bell, P. R. F.</creatorcontrib><description>The accurate clinical diagnosis of acute appendicitis is dificult, and many techniques have been suggested to improve diagnostic accuracy such as laparoscopy, ultrasonography and barium enema examination. In this study serial total leucocyte counts and serial C‐reactive protein (CRP) concentrations in acute appendicitis were measured. The sensitivity and specificity of serial leucocyte counts in acute appendicitis were 92 and 100 per cent, and for CRP concentrations 69 and 75 per cent, respectively. The sensitivity and specificity of serial total leucocyte counts fulfilled the criteria for a diagnostic test. It is suggested that in patients with equivocal clinical findings, clinical observation combined with serial leucocyte counts may improve decision making.</description><identifier>ISSN: 0007-1323</identifier><identifier>EISSN: 1365-2168</identifier><identifier>DOI: 10.1002/bjs.1800790839</identifier><identifier>PMID: 1393485</identifier><identifier>CODEN: BJSUAM</identifier><language>eng</language><publisher>Bristol: John Wiley & Sons, Ltd</publisher><subject>Acute Disease ; Adolescent ; Adult ; Aged ; Appendicitis - blood ; Appendicitis - diagnosis ; Biological and medical sciences ; C-Reactive Protein - analysis ; Child ; Child, Preschool ; Diagnosis, Differential ; Female ; Gastroenterology. Liver. Pancreas. Abdomen ; Humans ; Leukocyte Count ; Leukocytosis - blood ; Male ; Medical sciences ; Middle Aged ; Other diseases. Semiology ; Sensitivity and Specificity ; Stomach. Duodenum. Small intestine. Colon. Rectum. Anus</subject><ispartof>British journal of surgery, 1992-08, Vol.79 (8), p.822-824</ispartof><rights>Copyright © 1992 British Journal of Surgery Society Ltd.</rights><rights>1992 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c2839-2b521ec1a3f72eac8c9c9678bd2a62d04be40df215e087c226484a0b3760371a3</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1002%2Fbjs.1800790839$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1002%2Fbjs.1800790839$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,780,784,1417,27924,27925,45574,45575</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=5449613$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/1393485$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Thompson, M. M.</creatorcontrib><creatorcontrib>Underwood, M. J.</creatorcontrib><creatorcontrib>Dookeran, K. A.</creatorcontrib><creatorcontrib>Lloyd, D. M.</creatorcontrib><creatorcontrib>Bell, P. R. F.</creatorcontrib><title>Role of sequential leucocyte counts and C-reactive protein measurements in acute appendicitis</title><title>British journal of surgery</title><addtitle>Br J Surg</addtitle><description>The accurate clinical diagnosis of acute appendicitis is dificult, and many techniques have been suggested to improve diagnostic accuracy such as laparoscopy, ultrasonography and barium enema examination. In this study serial total leucocyte counts and serial C‐reactive protein (CRP) concentrations in acute appendicitis were measured. The sensitivity and specificity of serial leucocyte counts in acute appendicitis were 92 and 100 per cent, and for CRP concentrations 69 and 75 per cent, respectively. The sensitivity and specificity of serial total leucocyte counts fulfilled the criteria for a diagnostic test. It is suggested that in patients with equivocal clinical findings, clinical observation combined with serial leucocyte counts may improve decision making.</description><subject>Acute Disease</subject><subject>Adolescent</subject><subject>Adult</subject><subject>Aged</subject><subject>Appendicitis - blood</subject><subject>Appendicitis - diagnosis</subject><subject>Biological and medical sciences</subject><subject>C-Reactive Protein - analysis</subject><subject>Child</subject><subject>Child, Preschool</subject><subject>Diagnosis, Differential</subject><subject>Female</subject><subject>Gastroenterology. Liver. Pancreas. Abdomen</subject><subject>Humans</subject><subject>Leukocyte Count</subject><subject>Leukocytosis - blood</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Other diseases. Semiology</subject><subject>Sensitivity and Specificity</subject><subject>Stomach. Duodenum. Small intestine. Colon. Rectum. Anus</subject><issn>0007-1323</issn><issn>1365-2168</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1992</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpFkUtPwzAMgCMEgvG4ckPqAXErOEmbtEcYMB4TCDbECUVp6kqBPkbTAvv3ZNq0nSLH32c7MSHHFM4pALvIPt05TQBkCglPt8iAchGHjIpkmwzA34eUM75H9p37BKAcYrZLdilPeZTEA_Lx2pQYNEXg8LvHurO6DErsTWPmHQam6evOBbrOg2HYojad_cFg1jYd2jqoULu-xQoXjI-16b2jZzOsc2tsZ90h2Sl06fBodR6Qt9ub6fAuHD-P7oeX49AwP3TIsphRNFTzQjLfJTGpSYVMspxpwXKIMowgLxiNERJpGBNREmnIuBTApdcOyNmyrh_NP8N1qrLOYFnqGpveKcm9IyD14MkK7LMKczVrbaXbuVr9h8-frvLaGV0Wra6NdWssjqJUUO6xdIn92hLnmyqgFjtRfidqsxN19TDZRN4Nl651Hf6tXd1-KSG5jNX700hF0-vbx4kE9cL_AWIhjzs</recordid><startdate>199208</startdate><enddate>199208</enddate><creator>Thompson, M. M.</creator><creator>Underwood, M. J.</creator><creator>Dookeran, K. A.</creator><creator>Lloyd, D. M.</creator><creator>Bell, P. R. F.</creator><general>John Wiley & Sons, Ltd</general><general>Wiley</general><scope>BSCLL</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope></search><sort><creationdate>199208</creationdate><title>Role of sequential leucocyte counts and C-reactive protein measurements in acute appendicitis</title><author>Thompson, M. M. ; Underwood, M. J. ; Dookeran, K. A. ; Lloyd, D. M. ; Bell, P. R. F.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c2839-2b521ec1a3f72eac8c9c9678bd2a62d04be40df215e087c226484a0b3760371a3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1992</creationdate><topic>Acute Disease</topic><topic>Adolescent</topic><topic>Adult</topic><topic>Aged</topic><topic>Appendicitis - blood</topic><topic>Appendicitis - diagnosis</topic><topic>Biological and medical sciences</topic><topic>C-Reactive Protein - analysis</topic><topic>Child</topic><topic>Child, Preschool</topic><topic>Diagnosis, Differential</topic><topic>Female</topic><topic>Gastroenterology. Liver. Pancreas. Abdomen</topic><topic>Humans</topic><topic>Leukocyte Count</topic><topic>Leukocytosis - blood</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Other diseases. Semiology</topic><topic>Sensitivity and Specificity</topic><topic>Stomach. Duodenum. Small intestine. Colon. Rectum. Anus</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Thompson, M. M.</creatorcontrib><creatorcontrib>Underwood, M. J.</creatorcontrib><creatorcontrib>Dookeran, K. A.</creatorcontrib><creatorcontrib>Lloyd, D. M.</creatorcontrib><creatorcontrib>Bell, P. R. F.</creatorcontrib><collection>Istex</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><jtitle>British journal of surgery</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Thompson, M. M.</au><au>Underwood, M. J.</au><au>Dookeran, K. A.</au><au>Lloyd, D. M.</au><au>Bell, P. R. F.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Role of sequential leucocyte counts and C-reactive protein measurements in acute appendicitis</atitle><jtitle>British journal of surgery</jtitle><addtitle>Br J Surg</addtitle><date>1992-08</date><risdate>1992</risdate><volume>79</volume><issue>8</issue><spage>822</spage><epage>824</epage><pages>822-824</pages><issn>0007-1323</issn><eissn>1365-2168</eissn><coden>BJSUAM</coden><abstract>The accurate clinical diagnosis of acute appendicitis is dificult, and many techniques have been suggested to improve diagnostic accuracy such as laparoscopy, ultrasonography and barium enema examination. In this study serial total leucocyte counts and serial C‐reactive protein (CRP) concentrations in acute appendicitis were measured. The sensitivity and specificity of serial leucocyte counts in acute appendicitis were 92 and 100 per cent, and for CRP concentrations 69 and 75 per cent, respectively. The sensitivity and specificity of serial total leucocyte counts fulfilled the criteria for a diagnostic test. It is suggested that in patients with equivocal clinical findings, clinical observation combined with serial leucocyte counts may improve decision making.</abstract><cop>Bristol</cop><pub>John Wiley & Sons, Ltd</pub><pmid>1393485</pmid><doi>10.1002/bjs.1800790839</doi><tpages>3</tpages></addata></record> |
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| subjects | Acute Disease Adolescent Adult Aged Appendicitis - blood Appendicitis - diagnosis Biological and medical sciences C-Reactive Protein - analysis Child Child, Preschool Diagnosis, Differential Female Gastroenterology. Liver. Pancreas. Abdomen Humans Leukocyte Count Leukocytosis - blood Male Medical sciences Middle Aged Other diseases. Semiology Sensitivity and Specificity Stomach. Duodenum. Small intestine. Colon. Rectum. Anus |
| title | Role of sequential leucocyte counts and C-reactive protein measurements in acute appendicitis |
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