Direct evidence for the activation of phospholipase C gamma 1 by in vivo treatment with morphine in the mouse periaqueductal gray matter

The aim of the present study was to investigate whether in vivo morphine treatment could participate in the activation of phospholipase Cgamma1 (PLCgamma1) isoform in the mouse periaqueductal gray matter (PAG) which can be accompanied by antinociceptive responses induced by morphine. As well as mu-o...

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Veröffentlicht in:	Brain research 2003-04, Vol.970 (1-2), p.140-148
Hauptverfasser:	Narita, Minoru, Ohnishi, Orie, Narita, Michiko, Aoki, Takeshi, Suzuki, Masami, Yajima, Yoshinori, Funahashi, Hisayuki, Shioda, Seiji, Suzuki, Tsutomu
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Dose-Response Relationship, Drug Enzyme Activation - drug effects Enzyme Activation - physiology Male Mice Morphine - pharmacology Periaqueductal Gray - chemistry Periaqueductal Gray - drug effects Periaqueductal Gray - enzymology Phospholipase C gamma Type C Phospholipases - analysis Type C Phospholipases - metabolism
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