Interleukin-6 Enhances Whereas Tumor Necrosis Factor α and Interferons Inhibit Integrin Expression and Adhesion of Human Mast Cells to Extracellular Matrix Proteins

Integrins are expressed on mast cells and constitute an essential prerequisite for the accumulation of the cells at sites of inflammation. In order to clarify a potential contribution of inflammatory cytokines to this process, we have studied the modulation of integrin expression and adhesion of imm...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Journal of investigative dermatology 2003-05, Vol.120 (5), p.795-801
Hauptverfasser:	Schoeler, Dagmar, Grützkau, Andreas, Henz, Beate M., Küchler, Jens, Krüger-Krasagakis, Sabine
Format:	Artikel
Sprache:	eng
Schlagworte:	Adrenal Cortex Hormones - metabolism Anti-Inflammatory Agents - pharmacology Biological and medical sciences Cell Adhesion Cell Separation corticosteroids Dermatology Dexamethasone - pharmacology Down-Regulation Extracellular Matrix - metabolism fibronectin Flow Cytometry HMC-1 cells Humans Integrin alpha2 - biosynthesis Integrin alpha5 - biosynthesis Integrin alpha6 - biosynthesis Integrin alphaV - biosynthesis Integrins - metabolism Interferon-alpha - metabolism Interferon-gamma - pharmacology Interferons - metabolism Interleukin-6 - metabolism Investigative techniques, diagnostic techniques (general aspects) laminin Mast Cells - cytology Medical sciences Pathology. Cytology. Biochemistry. Spectrometry. Miscellaneous investigative techniques Polymerase Chain Reaction Receptors, Glucocorticoid - metabolism Reverse Transcriptase Polymerase Chain Reaction RNA, Messenger - metabolism Tumor Necrosis Factor-alpha - metabolism vitronectin
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!