The use of acute normovolemic hemodilution in patients undergoing cardiac surgery
Avoiding allogeneic blood transfusion during cardiac surgery and during the post-operative period is of great importance. Acute normovolemic hemodilution (ANH) is one of the options for blood salvage. We have prospectively analyzed 310 consecutive patients (pts) after different open heart procedures...
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| Veröffentlicht in: | Cardiovascular surgery (London, England) England), 2003-06, Vol.11 (3), p.201-205 |
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| creator | Jović, Miomir Ð Čalija, Branko M Radomir, Boško J Perić, Miodrag S Krivokapić, Borislav N Jagodić, Siniša P Babić, Milan J Ðukanović, Boško P |
| description | Avoiding allogeneic blood transfusion during cardiac surgery and during the post-operative period is of great importance. Acute normovolemic hemodilution (ANH) is one of the options for blood salvage. We have prospectively analyzed 310 consecutive patients (pts) after different open heart procedures, operated on during April–May, 2000. ANH was possible in 226 pts (73%) with hemoglobin level over 125 g/l and hematocrit over 36%. Of those, one unit of blood was withdrawn in 128 pts (70%), while two to five units of blood were taken in 68 pts (30%). Total number of autologous blood units taken was 296, for the average of 1.31 units/pt. Predictors of increased intra- and post-operative blood loss were hematocrit (Hct) |
| doi_str_mv | 10.1016/S0967-2109(03)00020-6 |
| format | Article |
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p<0.001), age over 65 (
p=0.028), female sex (
p=0.006), CPB duration over 90 min (63% vs. 37%;
p<0.001) and preoperative left ventricular ejection fraction (LVEF) <35% (63% vs. 37%;
p<0.001). All pts with the above-mentioned characteristics were in need for allogeneic blood transfusion. During their hospital stay, 142 pts did not get allogeneic blood (142/310, 46%), and all were in the ANH group (142/226, 62%).</description><identifier>ISSN: 0967-2109</identifier><identifier>DOI: 10.1016/S0967-2109(03)00020-6</identifier><identifier>PMID: 12704329</identifier><language>eng</language><publisher>England: Elsevier Ltd</publisher><subject>acute normovolemic hemodilution ; Blood Transfusion ; Blood Volume ; cardiac surgery ; Female ; Heart Diseases - surgery ; Hematocrit ; Hemodilution ; Hemoglobins - analysis ; Hemostasis, Surgical ; Humans ; Intraoperative Period ; Male ; Middle Aged ; Prospective Studies ; Transplantation, Autologous</subject><ispartof>Cardiovascular surgery (London, England), 2003-06, Vol.11 (3), p.201-205</ispartof><rights>2003 The International Society for Cardiovascular Surgery</rights><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c361t-c12d4da00383de433a74479d4fb9379e6422b3f4224fa4a7c14835eae5896e253</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27903,27904</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/12704329$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Jović, Miomir Ð</creatorcontrib><creatorcontrib>Čalija, Branko M</creatorcontrib><creatorcontrib>Radomir, Boško J</creatorcontrib><creatorcontrib>Perić, Miodrag S</creatorcontrib><creatorcontrib>Krivokapić, Borislav N</creatorcontrib><creatorcontrib>Jagodić, Siniša P</creatorcontrib><creatorcontrib>Babić, Milan J</creatorcontrib><creatorcontrib>Ðukanović, Boško P</creatorcontrib><title>The use of acute normovolemic hemodilution in patients undergoing cardiac surgery</title><title>Cardiovascular surgery (London, England)</title><addtitle>Cardiovasc Surg</addtitle><description>Avoiding allogeneic blood transfusion during cardiac surgery and during the post-operative period is of great importance. Acute normovolemic hemodilution (ANH) is one of the options for blood salvage. We have prospectively analyzed 310 consecutive patients (pts) after different open heart procedures, operated on during April–May, 2000. ANH was possible in 226 pts (73%) with hemoglobin level over 125 g/l and hematocrit over 36%. Of those, one unit of blood was withdrawn in 128 pts (70%), while two to five units of blood were taken in 68 pts (30%). Total number of autologous blood units taken was 296, for the average of 1.31 units/pt. Predictors of increased intra- and post-operative blood loss were hematocrit (Hct) <39% (76% vs. 24%,
p<0.001), age over 65 (
p=0.028), female sex (
p=0.006), CPB duration over 90 min (63% vs. 37%;
p<0.001) and preoperative left ventricular ejection fraction (LVEF) <35% (63% vs. 37%;
p<0.001). All pts with the above-mentioned characteristics were in need for allogeneic blood transfusion. During their hospital stay, 142 pts did not get allogeneic blood (142/310, 46%), and all were in the ANH group (142/226, 62%).</description><subject>acute normovolemic hemodilution</subject><subject>Blood Transfusion</subject><subject>Blood Volume</subject><subject>cardiac surgery</subject><subject>Female</subject><subject>Heart Diseases - surgery</subject><subject>Hematocrit</subject><subject>Hemodilution</subject><subject>Hemoglobins - analysis</subject><subject>Hemostasis, Surgical</subject><subject>Humans</subject><subject>Intraoperative Period</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Prospective Studies</subject><subject>Transplantation, Autologous</subject><issn>0967-2109</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2003</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkE1LAzEQhnNQbK3-BCUn0cNqsslmm5NI8QsKItZzSJPZNrK7qcmm0H_v9gM9epmB4XlnmAehC0puKaHi7oNIUWY5JfKasBtCSE4ycYSGv-MBOo3xi_SsZOMTNKB5STjL5RC9z5aAUwTsK6xN6gC3PjR-7WtonMFLaLx1deqcb7Fr8Up3Dtou4tRaCAvv2gU2OlinDY4pLCBsztBxpesI54c-Qp9Pj7PJSzZ9e36dPEwzwwTtMkNzy60mhI2ZBc6YLjkvpeXVXLJSguB5PmdVX3mluS4N5WNWgIZiLAXkBRuhq_3eVfDfCWKnGhcN1LVuwaeoStZHhRA9WOxBE3yMASq1Cq7RYaMoUVt_audPbUUpwtTOn9rmLg8H0rwB-5c6yOuB-z0A_ZtrB0FF09sxYF0A0ynr3T8nfgAeboHj</recordid><startdate>20030601</startdate><enddate>20030601</enddate><creator>Jović, Miomir Ð</creator><creator>Čalija, Branko M</creator><creator>Radomir, Boško J</creator><creator>Perić, Miodrag S</creator><creator>Krivokapić, Borislav N</creator><creator>Jagodić, Siniša P</creator><creator>Babić, Milan J</creator><creator>Ðukanović, Boško P</creator><general>Elsevier Ltd</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20030601</creationdate><title>The use of acute normovolemic hemodilution in patients undergoing cardiac surgery</title><author>Jović, Miomir Ð ; Čalija, Branko M ; Radomir, Boško J ; Perić, Miodrag S ; Krivokapić, Borislav N ; Jagodić, Siniša P ; Babić, Milan J ; Ðukanović, Boško P</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c361t-c12d4da00383de433a74479d4fb9379e6422b3f4224fa4a7c14835eae5896e253</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2003</creationdate><topic>acute normovolemic hemodilution</topic><topic>Blood Transfusion</topic><topic>Blood Volume</topic><topic>cardiac surgery</topic><topic>Female</topic><topic>Heart Diseases - surgery</topic><topic>Hematocrit</topic><topic>Hemodilution</topic><topic>Hemoglobins - analysis</topic><topic>Hemostasis, Surgical</topic><topic>Humans</topic><topic>Intraoperative Period</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Prospective Studies</topic><topic>Transplantation, Autologous</topic><toplevel>online_resources</toplevel><creatorcontrib>Jović, Miomir Ð</creatorcontrib><creatorcontrib>Čalija, Branko M</creatorcontrib><creatorcontrib>Radomir, Boško J</creatorcontrib><creatorcontrib>Perić, Miodrag S</creatorcontrib><creatorcontrib>Krivokapić, Borislav N</creatorcontrib><creatorcontrib>Jagodić, Siniša P</creatorcontrib><creatorcontrib>Babić, Milan J</creatorcontrib><creatorcontrib>Ðukanović, Boško P</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Cardiovascular surgery (London, England)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Jović, Miomir Ð</au><au>Čalija, Branko M</au><au>Radomir, Boško J</au><au>Perić, Miodrag S</au><au>Krivokapić, Borislav N</au><au>Jagodić, Siniša P</au><au>Babić, Milan J</au><au>Ðukanović, Boško P</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>The use of acute normovolemic hemodilution in patients undergoing cardiac surgery</atitle><jtitle>Cardiovascular surgery (London, England)</jtitle><addtitle>Cardiovasc Surg</addtitle><date>2003-06-01</date><risdate>2003</risdate><volume>11</volume><issue>3</issue><spage>201</spage><epage>205</epage><pages>201-205</pages><issn>0967-2109</issn><abstract>Avoiding allogeneic blood transfusion during cardiac surgery and during the post-operative period is of great importance. Acute normovolemic hemodilution (ANH) is one of the options for blood salvage. We have prospectively analyzed 310 consecutive patients (pts) after different open heart procedures, operated on during April–May, 2000. ANH was possible in 226 pts (73%) with hemoglobin level over 125 g/l and hematocrit over 36%. Of those, one unit of blood was withdrawn in 128 pts (70%), while two to five units of blood were taken in 68 pts (30%). Total number of autologous blood units taken was 296, for the average of 1.31 units/pt. Predictors of increased intra- and post-operative blood loss were hematocrit (Hct) <39% (76% vs. 24%,
p<0.001), age over 65 (
p=0.028), female sex (
p=0.006), CPB duration over 90 min (63% vs. 37%;
p<0.001) and preoperative left ventricular ejection fraction (LVEF) <35% (63% vs. 37%;
p<0.001). All pts with the above-mentioned characteristics were in need for allogeneic blood transfusion. During their hospital stay, 142 pts did not get allogeneic blood (142/310, 46%), and all were in the ANH group (142/226, 62%).</abstract><cop>England</cop><pub>Elsevier Ltd</pub><pmid>12704329</pmid><doi>10.1016/S0967-2109(03)00020-6</doi><tpages>5</tpages></addata></record> |
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| subjects | acute normovolemic hemodilution Blood Transfusion Blood Volume cardiac surgery Female Heart Diseases - surgery Hematocrit Hemodilution Hemoglobins - analysis Hemostasis, Surgical Humans Intraoperative Period Male Middle Aged Prospective Studies Transplantation, Autologous |
| title | The use of acute normovolemic hemodilution in patients undergoing cardiac surgery |
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