Neural mechanism of propofol anesthesia in severe depression: A positron emission tomographic study

The precise neural mechanisms of propofol anesthesia in humans are still unknown. The authors examined the acute effects of propofol on regional cerebral blood flow (rCBF) using positron emission tomography in patients with severe depression. In six severely depressed patients (mean age, 55.0 yr) sc...

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Veröffentlicht in:	Anesthesiology (Philadelphia) 2003-05, Vol.98 (5), p.1101-1111
Hauptverfasser:	OGAWA, Kenichi, UEMA, Takeshi, TAKEDA, Masatoshi, MATSUDA, Hiroshi, ANDOH, Tomio, YAMADA, Yoshitsugu, MOTOHASHI, Nobutaka, NISHIKAWA, Masami, TAKANO, Harumasa, HIROKI, Masahiko, IMABAYASHI, Etsuko, OHNISHI, Takashi, INOUE, Tomio, TAKAYAMA, Yutaka
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Anesthesia Anesthetics, Intravenous - pharmacokinetics Anesthetics, Intravenous - pharmacology Anesthetics. Neuromuscular blocking agents Biological and medical sciences Blood Flow Velocity - drug effects Brain - diagnostic imaging Brain Mapping Cerebrovascular Circulation - drug effects Conscious Sedation Depressive Disorder - diagnostic imaging Depressive Disorder - physiopathology Depressive Disorder - therapy Electroconvulsive Therapy Female Hemodynamics - drug effects Hemodynamics - physiology Humans Male Medical sciences Middle Aged Neuropharmacology Pharmacology. Drug treatments Propofol - pharmacokinetics Propofol - pharmacology Radiography Tomography, Emission-Computed Wakefulness
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