Dopamine and melatonin in the nucleus accumbens may be implicated in the mode of action of antidepressant drugs

The effect of chronic systemic treatment (once a day for 2–3 weeks) with different antidepressant drugs (desipramine, mianserin, fluvoxamine 15 mg/kg per day i.p. or s.c.) on the behavioral responses elicited by intra-accumbens injection of graded doses (1–10 000 ng) of apomorphine and two doses (10...

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