Factor Xa interacts with two sites on monocytes with different functional activities

Studies were performed to elucidate the functional significance of factor Xa interactions at the monocyte membrane in the presence and absence of factor Va, with respect to prothrombin and factor IX cleavage. Factor Xa-catalyzed prothrombin activation at the monocyte surface was absolutely dependent...

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Veröffentlicht in:	Blood 1992-10, Vol.80 (8), p.1989-1997
Hauptverfasser:	WORFOLK, L. A, ROBINSON, R. A, TRACY, P. B
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibodies, Monoclonal Binding Sites Biological and medical sciences Blood coagulation. Blood cells Blood Platelets - metabolism Cell Membrane - metabolism Coagulation factors Electrophoresis, Polyacrylamide Gel Factor IX - metabolism Factor V - immunology Factor Va - pharmacology Factor Xa - metabolism Fundamental and applied biological sciences. Psychology Humans Kinetics Molecular and cellular biology Monocytes - metabolism Prothrombin - metabolism Thrombin - metabolism
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