Disodium ascorbyl phytostanyl phosphate reduces plasma cholesterol concentrations and atherosclerotic lesion formation in apolipoprotein E-deficient mice

Disodium ascorbyl phytostanyl phosphate (FM-VP4) consists of ascorbic acid covalently bound to phytostanols by a phosphodiester linkage and is derived as the disodium salt. The purpose of this study was to evaluate the lipid-lowering and antiatherosclerotic properties of FM-VP4 following administrat...

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Veröffentlicht in:	Metabolism, clinical and experimental clinical and experimental, 2003-04, Vol.52 (4), p.425-431
Hauptverfasser:	Lukic, Tatjana, Wasan, Kishor M., Zamfir, Daniela, Moghadasian, Mohammed H., Pritchard, P.Haydn
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Anticholesteremic Agents - pharmacology Apolipoproteins E - deficiency Apolipoproteins E - genetics Arteriosclerosis - drug therapy Arteriosclerosis - pathology Ascorbic Acid - pharmacology Biological and medical sciences Cholesterol - blood Diet Disorders of blood lipids. Hyperlipoproteinemia Dose-Response Relationship, Drug General and cellular metabolism. Vitamins Histocytochemistry Image Processing, Computer-Assisted Male Medical sciences Metabolic diseases Mice Mice, Inbred C57BL Pharmacology. Drug treatments Phytosterols - pharmacology Triglycerides - blood
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