Receptors for interleukin 2 on human squamous cell carcinoma cell lines and tumor in situ

Several human head and neck squamous carcinoma cell lines were found to bind 125I-labeled or fluorescein-labeled interleukin 2 (IL-2). This binding was inhibited by an excess of cold ligand, IL-2, and by anti-p55 and anti-p70 monoclonal antibodies to the alpha and beta chains, respectively, of the I...

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Veröffentlicht in:	Cancer research (Chicago, Ill.) Ill.), 1992-11, Vol.52 (21), p.5963-5970
Hauptverfasser:	WEIDMANN, E, SACCHI, M, PLAISANCE, S, DAE SEOG HEO, YASUMURA, S, WEN-CHANG LIN, JOHNSON, J. T, HERBERMAN, R. B, AZZARONE, B, WHITESIDE, T. L
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibodies, Monoclonal - pharmacology Base Sequence Binding, Competitive Biological and medical sciences Carcinoma, Squamous Cell - chemistry Carcinoma, Squamous Cell - metabolism Carcinoma, Squamous Cell - therapy Flow Cytometry Head and Neck Neoplasms - chemistry Head and Neck Neoplasms - metabolism Head and Neck Neoplasms - therapy Humans Interleukin-2 - pharmacology Keratinocytes - chemistry Medical sciences Molecular Sequence Data Otorhinolaryngology (head neck, general aspects and miscellaneous) Otorhinolaryngology. Stomatology Receptors, Interleukin-2 - analysis Receptors, Interleukin-2 - immunology Receptors, Interleukin-2 - metabolism RNA, Messenger - analysis Tumor Cells, Cultured Tumors
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